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Bariatric intervention significantly reduced BMI and intrahepatic fat in patients with obesity, leading to improvements in histologic features of metabolic dysfunction-associated steatohepatitis. Nonalcoholic fatty liver disease activity score decreased significantly at various time points post-intervention. These findings suggest that bariatric intervention may be an effective…
Analysis of revisional and conversional sleeve gastrectomy procedures with concurrent hiatal hernia repair showed increased operative time, risk of postoperative pneumonia, and readmission within thirty days for patients with hiatal hernia repair. Despite these findings, patients undergoing laparoscopic revisional or conversional sleeve gastrectomy with hiatal…
Individuals with lower polygenic risk scores experienced better weight loss outcomes after bariatric surgery compared to those with higher scores, especially in patients undergoing roux-en-y gastric bypass. Genetic background, assessed through polygenic risk scores, plays a significant role in long-term weight loss post-surgery, alongside factors…
Significant weight loss and remission of type 2 diabetes mellitus were observed in patients post-sleeve gastrectomy. Patients exhibited low citrulline and high I-FABP levels preoperatively, which normalized postoperatively. The study found a positive correlation between the I-FABP/citrulline ratio and weight, BMI, glucose, insulin, and c-peptide…
Male patients had slightly greater weight loss and higher complication rates compared to females following bariatric surgery. However, these differences were not clinically significant. Providers should consider referring males earlier for surgery given their higher comorbidity rates. This study highlights the need to assess sex…
Findings from the BAMBINI trial show that bariatric surgery significantly increased rates of spontaneous ovulation in women with polycystic ovary syndrome (PCOS) and obesity compared to medical care. The surgical group had 2.5 times more ovulations than the medical group, indicating greater efficacy in improving…
One anastomosis gastric bypass (OAGB) and sleeve gastrectomy with loop duodenojejunal bypass (SG + LoopDJB) demonstrate similar weight loss, type 2 diabetes remission, and lipidemia improvements at 1 year post-operation. OAGB presents higher hypoalbuminemia but lower gastroesophageal reflux disease symptoms compared to SG + LoopDJB.…
Preoperative risk factors, including age, gender, hypertension, and revisional bariatric surgery, are associated with early postoperative bleeding after Roux-en-Y gastric bypass. Further primary studies are needed to explore additional risk factors for this complication, aiding in patient risk stratification and optimization. Male gender was identified…
Patients with obesity undergoing surgery face higher risks, mitigated by preoperative weight loss strategies like very low-energy diets (VLEDs) commonly used in bariatric surgery. However, VLEDs' application in non-bariatric surgery is understudied. A pilot trial is needed to assess feasibility and safety for a larger…
Metabolic bariatric surgery shows enduring weight reduction and improvement in obesity-related comorbidities. Both OAGB and SADJB-SG procedures lead to significant improvements in BMI, diabetes, hypertension, and dyslipidemia over three years. Patients also experience a substantial reduction in 10-year MACE, stroke, and atherosclerotic CVD risks. These…
