A meta-analysis revealed that sleeve gastrectomy (SG) significantly reduces the apnea-hypopnea index (AHI), body mass index (BMI), weight, and fat areas while enhancing forced vital capacity (FVC) and sleep metrics in patients with obesity and obstructive sleep apnea (OSA). Key post-surgical benefits included decreased arousal index, oxygen desaturation index (ODI), and improvements in metabolic markers […]
Category: Metabolic and Bariatric Surgery
Identification of six hub genes for NAFLD treatment
Comprehensive machine learning facilitated the identification of 12 consensus predicted genes (CPGs) linked to non-alcoholic fatty liver disease (NAFLD) following metabolic and bariatric surgery (MBS). A mouse model confirmed the mRNA expression of six hub genes—PPARA, PLIN2, MED13, INSIG1, CPT1A, and ALOX5AP—showing strong correlations with data from three validation datasets. These findings highlight the potential […]
Sleeve gastrectomy reduces all-cause mortality compared to RYGB.
In adults with morbid obesity, sleeve gastrectomy (SG) significantly lowers all-cause mortality risks during follow-up compared to Roux-en-Y gastric bypass (RYGB). A systematic review and meta-analysis of 22 studies involving 333,713 patients revealed that SG is linked to reduced reoperation, reintervention, and hospitalization rates, although it has a higher revision rate. These findings underscore the […]
Consensus established for safe practices in bariatric surgery tourism
Healthcare professionals and patient representatives have reached a consensus on safe practices for bariatric and metabolic surgery tourism (BMT) in Europe. Key recommendations emphasize the importance of pre-operative evaluations, management of psychological health, and regulatory standards like surgeon accreditation. With input from 119 healthcare professionals and 88 patient representatives across 26 countries, the consensus aims […]
Sleeve gastrectomy significantly improves metabolic outcomes in patients.
Sleeve gastrectomy has shown profound benefits for metabolic health in a cohort of 199 patients, revealing significant reductions in weight, BMI, and abdominal circumference. Notable improvements in diabetic patients included decreases in fasting blood sugar and glycosylated hemoglobin levels, alongside a marked reduction in insulin resistance and serum insulin. Additionally, enhancements in lipid profiles and […]
Surgical technique influences risk of gastroesophageal reflux after surgery
Surgical techniques during laparoscopic sleeve gastrectomy significantly affect the development of gastroesophageal reflux disease (GERD). Analyzing 7,435 patients, the study found that using a narrower bougie size and resecting further from the pylorus increased the likelihood of requiring proton pump inhibitors (PPIs) post-surgery. Advanced age and female sex were identified as independent risk factors for […]
Bariatric surgery significantly reduces cancer risk in obese patients
A systematic review and meta-analysis of 21 studies revealed that metabolic and bariatric surgeries (MBS) substantially lower cancer risk in obese patients compared to non-surgical treatments. Specifically, MBS showed protective effects against colorectal (mean effect size -.28), uterine (mean effect size -.42), breast (mean effect size -.37), and esophageal cancers (mean effect size -.23). Overall, […]
Bariatric surgery significantly reduces long-term mortality in cirrhosis patients
In a retrospective cohort study of 91,708 patients with metabolic dysfunction-associated steatotic liver disease and cirrhosis, bariatric surgery markedly decreased mortality risks. Those who underwent the procedure showed a 5-year overall mortality of 24.9%, compared to 37.1% in non-surgical counterparts. Significant reductions were also observed in liver-related (3.3% vs. 14%) and non-liver-related mortality (22.3% vs. […]
Enhanced Recovery Program Improves Outcomes in Bariatric Surgery
Implementation of the Enhanced Recovery After Surgery (ERAS) program in bariatric procedures significantly reduced hospital stay, costs, and unplanned readmissions. A study comparing pre-ERAS and post-ERAS cohorts revealed a median length of stay decrease by one day and an average cost reduction of $2,230. Additionally, the post-ERAS group exhibited a 52% lower risk of 30-day […]
Roux-en-Y gastric bypass outperforms sleeve gastrectomy in long-term hypertension remission
A systematic review of 11 randomized controlled trials involving 2,323 patients indicates that both sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) show comparable hypertension remission within the first four years post-surgery. However, RYGB demonstrated a significantly greater effectiveness in achieving remission at five years or more, with a relative risk of 1.39. These findings […]
