Newsletter
Best Papers in General Surgery
The five that matter, every day.
An international survey reveals that 91.6% of surgeons advocate for preoperative chemotherapy in initially unresectable intrahepatic cholangiocarcinoma (ICCA). Most cite tumor downstaging and selecting favorable cases for R0 resection as major benefits. Key concerns defining unresectability include insufficient future liver remnant volume and inability to…
Practical, evidence-based strategies to shorten ileus and length of stay
Timing of stoma reversal plays a critical role in patient outcomes. In a retrospective cohort study of 505 patients, those reversed within 18 months experienced significantly lower complication rates (7.9% vs. 35.1%) and shorter hospital stays (6 days vs. 7 days). Alarmingly, 28.9% underwent reversal,…
Innovations in endoscopic resection now enable the safe removal of larger and deeper gastric subepithelial lesions (SELs), previously suitable only for surgical intervention. This article outlines various endoscopic modalities and provides crucial technical tips. In a case series, successful en bloc resections were achieved in…
Artificial intelligence significantly enhances endoscopic precision, outperforming human detection rates, particularly in polyp identification. Systems like GI Genius demonstrate remarkable sensitivity and specificity, while convolutional neural networks facilitate real-time classification of lesions. Furthermore, AI streamlines workflows through automated reporting and training tools. Despite these advancements,…
Patients with very early intrahepatic cholangiocarcinoma (ICC) show significant long-term survival, with 1-, 3-, and 5-year overall survival rates at 92.3%, 72.6%, and 58.0%, respectively. However, elevated carbohydrate antigen 19-9 (CA19-9) levels correlate with worse overall and recurrence-free survival rates, indicating more aggressive tumor features.…
Surgical resection post-systemic therapy for hepatocellular carcinoma (HCC) yields encouraging long-term outcomes. In a cohort of 96 patients, median overall survival reached four years, with one-year survival rates at 86.1%. R0/R1 resection correlated with improved progression-free and overall survival, presenting a significant therapeutic advantage. Complications…
One year post-bariatric surgery, 80% of patients showed a notable improvement in the nonalcoholic fatty liver disease (NAFLD) activity score. Nonalcoholic steatohepatitis (NASH) improved in 42.1% without worsening fibrosis, and 78.8% experienced fibrosis improvement. MRI-proton density fat fraction (MRI-PDFF) reliably detected liver fat remission in…
In older adults undergoing non-cardiac surgery, frailty significantly predicts postoperative complications, with a twofold increase in risk. While malnutrition also elevates risk, its impact is typically mediated by frailty. Analysis of 637 patients found frailty in 38.5% and malnutrition in 29.8%. Integrating both assessments effectively…
A novel AI tool, ENDOLAP, accurately classifies inflammation severity during laparoscopic cholecystectomy, addressing the subjectivity of current assessments. With an impressive overall accuracy of 87.3% and high sensitivity for severe cases (91.3%), it offers real-time decision support and reduces interobserver variability, which plagued 17% of…
