Newsletter
Best Papers in General Surgery
The five that matter, every day.
A novel recurrence risk model (rpv) effectively identifies stage II colon cancer patients who will benefit from adjuvant chemotherapy (AC). Analysis of cohorts from the U.S., Japan, Denmark, and Jordan reveals that high-risk patients achieving higher five-year recurrence-free survival (RFS) rates with AC—76.2% in cohort…
A surgical infection prevention program first proven in Ethiopia scaled successfully to five low-resource hospitals in Liberia, Madagascar, Malawi, India, and Bolivia. Among 1,865 surgical patients, 30-day surgical site infections dropped from 28.4% to 12.1%—a 49% relative reduction. Compliance with WHO checklist use, antibiotic timing,…
In a comparative study of neuromonitoring techniques during transoral thyroidectomy, percutaneous continuous vagal stimulation (PC) demonstrated superior performance over the conventional peroral delta electrode method. The PC group achieved faster electrode positioning, fewer displacement issues, and more reliable EMG signals. While both groups faced traction-related…
Endoscopic submucosal dissection (ESD) proves highly effective in treating GERD-related neoplasms, achieving a 100% en bloc resection rate and a 95.8% curative resection rate among 96 patients. Remarkably, no local recurrences or metastases were observed during follow-ups. After six months, nearly 70% of patients experienced…
Laparoscopic repeat liver resection (LRLR) significantly reduces intraoperative blood loss, complications, and hospital stays compared to open repeat liver resection (ORLR) for recurrent liver cancer. LRLR boasts a higher R0 resection rate, making it a safer, more effective option for patients. While operative time, transfusion…
A novel minimal important difference (MID) for the Comprehensive Complication Index (CCI) offers clarity on surgical outcomes for major abdominal surgery patients. Analyzing data from 1,583 patients across four studies, findings reveal an MID of 12 points in the CCI crucial for interpreting clinical significance…
In a comprehensive multicenter trial involving 355 patients with type I congenital bile duct dilation, radical extrahepatic cyst excision, compared to subtotal excision, markedly improved long-term outcomes. The radical approach significantly reduced rates of recurrent cholangitis, pancreatitis, and readmission, leading to better quality of life…
Neoadjuvant immune checkpoint inhibitors boost pathological complete response rates in locally advanced rectal cancer, ranging from 25-62.5%. The clinical complete response rates also soared—hitting 100% in some cases of dMMR/MSI-H tumors. Sphincter preservation rates reached up to 100%. Despite promising outcomes, the evidence stems from…
A comprehensive analysis of 7,855 esophageal cancer cases in Denmark reveals crucial survival outcomes based on treatment strategies. Definitive chemoradiotherapy offers lower overall survival compared to surgery, yet outperforms palliative care. Interestingly, stage IVB patients undergoing surgery showed unexpectedly favorable survival. This research leverages the…
Low skeletal muscle gauge (SMG) significantly predicts higher 30-day and 90-day mortality following emergency laparotomy, with odds ratios of 2.12 and 2.64, respectively. Patients presenting with acute abdominal pain should undergo routine computed tomography reporting of body composition, as low SMG also correlates with prolonged…
