A significant association was found between behavioral health disorders and new persistent opioid use following major surgeries. Among 62,585 patients studied, 20.3% with behavioral health disorders developed persistent opioid use compared to 16.6% without. This group also required higher median morphine doses. Additionally, those with behavioral health disorders had 32% greater odds of developing new […]
Category: General Surgery
New prognostic score improves survival predictions in gastric cancer
A novel prognostic oxidative stress-immune-inflammation score (posii score) has been developed to enhance survival predictions for gastric cancer patients post-radical gastrectomy. Analysis of 3,612 patients revealed that those in the low posii group exhibited significantly higher 5-year overall and disease-free survival rates, along with reduced recurrence risks (p < 0.05). Two validated online calculators based […]
Neoadjuvant immunochemotherapy shows promising outcomes in esophageal cancer.
A multicenter retrospective study evaluated neoadjuvant immunochemotherapy involving PD-1 agents plus platinum-based chemotherapy for 213 patients with resectable esophageal cancer. The study reported a high pathological complete response (PCR) rate of 31.9%, with a complete tumor resection (R0) rate of 99.1%. Additionally, two-year disease-free survival (DFS) and overall survival (OS) rates were notable at 78.9% […]
High accuracy in predicting clean common bile ducts
A study involving 584 acute biliary pancreatitis patients revealed that age, gamma-glutamyl transferase, alkaline phosphatase, and direct bilirubin levels significantly correlate with choledocholithiasis presence. The determined cut-off values indicated a 97% negative predictive value for a clean common bile duct when all four parameters were below thresholds. Consequently, unnecessary imaging could be minimized, leading to […]
Laparoscopic navigation improves outcomes in liver surgery
Laparoscopic portal territory fluorescence navigation-guided anatomical liver resection (LPTAR) outperforms classic anatomical resection (CAR) for hepatocellular carcinoma (HCC) patients. In a study of 234 patients, those undergoing LPTAR demonstrated significantly wider resection margins, reduced blood loss, and fewer postoperative complications compared to CAR. Furthermore, the recurrence-free survival rates at 1, 3, and 5 years were […]
EBV positivity improves survival rates in gastric cancer patients
In a multicenter study, significant differences in long-term survival were observed between patients with Epstein-Barr virus-associated gastric cancer (EBVAGC) and those with Epstein-Barr virus-negative gastric cancer (EBVNGC) after radical gastrectomy. The 3-year overall and disease-free survival rates were notably higher in the EBVAGC group. Additionally, positivity for Epstein-Barr virus-encoded small RNA served as an independent […]
Triclosan-Containing Sutures Reduce Surgical Site Infections
A recent systematic review and meta-analysis of 31 studies involving 17,968 participants demonstrated that triclosan-containing sutures substantially lower the incidence of surgical site infections compared to non-triclosan sutures, achieving a relative risk of 0.75 (95% CI, 0.65-0.86). Despite moderate certainty due to heterogeneity, the trial sequential analysis indicated that additional studies are unlikely to alter […]
Preoperative smoking cessation reduces postoperative complications in cancer surgery
This systematic review and meta-analysis involving 39,499 participants reveals that smokers who stopped smoking at least four weeks prior to cancer surgery experience significantly fewer complications. Those who smoked within four weeks before surgery faced 31% higher odds of complications, while those who never smoked had even greater risks, showing an odds ratio of 2.83. […]
Supraumbilical port reduces postoperative pain in gallbladder surgery
Laparoscopic cholecystectomy via the supraumbilical port significantly decreased postoperative pain compared to the subxiphoid port. In a study of 253 patients, the supraumbilical group reported lower worst pain ratings (4.24 vs. 4.91) and milder pain on the third day (3.35 vs. 3.75). Pain affected general activity, mood, walking ability, and enjoyment of life more severely […]
MUST emerges as the most valid nutritional screening tool
A multicentre study involving 1,649 patients assessed malnutrition risk in major abdominal surgeries. The Subjective Global Assessment (SGA) identified 34.1% as malnourished, while various tools showed significant variability in assessments. The Malnutrition Universal Screening Tool (MUST) and Mini Nutrition Assessment Short Form (MNA-SF) exhibited the best diagnostic capabilities. MUST demonstrated strong construct and prognostic validity, […]