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Best Papers in General Surgery
The five that matter, every day.
Surgical site infections (SSIs) pose a critical threat in low- and middle-income countries, affecting up to 25% of surgical patients. Limited resources and rising multidrug-resistant pathogens worsen the challenge. Tailored interventions, including active surveillance, revised surgical practices, and enhanced patient education, offer promising solutions. By…
Advanced age, inflammatory bowel disease, and higher ASA scores significantly reduce adherence to Enhanced Recovery After Surgery (ERAS) protocols in elective colorectal surgeries. Involving 656 patients, the study reveals that weakly non-adherent patients had fewer complications and shorter hospital stays compared to non-adherent peers. Specifically,…
Endoscopic suturing proves a game-changer for large Zenker's diverticula, leading to enhanced outcomes. A study of 75 patients revealed that those undergoing z-poem with endoscopic suturing faced no postoperative interventions, compared to a significant portion of patients with the clip closure option. The technical and…
Early assessment using the Glasgow Coma Scale motor score proves crucial for predicting mortality outcomes after trauma. A machine-learning model analyzing factors within three hours, 24 hours, and 30 days highlights the initial GCS motor score and worst GCS as consistent mortality predictors. Their efficacy…
Sarcopenia markedly increases the risk of major complications and lowers overall survival in patients with gastrointestinal cancer. An umbrella review of 63 studies reveals that 65% identify sarcopenia as a risk factor for severe postoperative issues, while 93% correlate it with diminished survival rates. With…
Robot-assisted hemihepatectomy outperforms laparoscopic techniques by significantly lowering intraoperative blood loss and reducing conversion to open surgery. An analysis of 1,113 patients revealed that while both approaches yielded similar operation times and complication rates, the robotic method exhibited distinct advantages. This comprehensive review consolidates findings…
ctDNA analysis predicts cancer recurrence and treatment efficacy in patients with resected stages I-III colon cancer. This large-scale, real-world study shows ctDNA positivity during the molecular residual disease (MRD) window correlates with significantly poorer disease-free survival (DFS). Patients who were ctDNA-positive at MRD and received…
The “real amylase value” (RAV) significantly outperforms traditional drain amylase concentration in predicting postoperative pancreatic fistula (POPF) risk. An analysis of 198 patients revealed RAV’s area under the ROC curve reached 0.85 on postoperative day 1 and 0.89 on day 3, compared to 0.79 for…
New radiomic prediction models effectively identify post-hepatectomy complications and early recurrences in hepatocellular carcinoma patients. Utilizing features from two-dimensional shear wave elastography, the comprehensive complication index (CCI) model achieved an AUC of 0.896, while the recurrence model reached 0.854. Key predictors included radiomic signatures, platelet…
Surgical treatment of complex benign colonic polyps significantly increases the risk of adverse events compared to endoscopy. An analysis of 240 patients revealed surgeries were linked to a higher likelihood of complications (odds ratio 3.27), severe adverse events (OR 7.5), and reinterventions (OR 25.6). Average…
