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General Surgery

Best Papers in General Surgery

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Medicine (Baltimore)14 Aug 2025

Low Phosphate Levels Heighten Complications Post-Pancreatic Surgery

Postoperative hypophosphatemia affects a significant 77.9% of pancreaticoduodenectomy patients, correlating with a 66.3% complication rate. The lowest phosphate levels occur on day three post-surgery, linking diminished phosphate to complications like pancreaticojejunostomy leakage. Those with complications show hypophosphatemia at a striking 82.5%. Monitoring and managing phosphate…

Surg Endosc13 Aug 2025

Preoperative Optimization Boosts Long-Term Health Post-Surgery

Preoperative optimization significantly improves long-term glucose control and smoking cessation for patients undergoing abdominal wall reconstruction. Among 51 optimized diabetic patients, glycated hemoglobin (HbA1c) dropped from 8.5 to 6.5 after a 10.6-month preoptimization period. Post-surgery, 63.2% maintained HbA1c ≤ 7.2. For smoking patients, 58.6% maintained…

Appendix, Gallbladder and Surgical Emergencies13 Aug 2025

Robotic Cholecystectomy Proves Safe for High-Risk Patients

Robotic cholecystectomy demonstrates safety and efficacy across various gallbladder pathologies in high-comorbidity patients, both elective and emergent. An analysis of 218 cases at a tertiary care facility from June 2020 to October 2023 revealed a 30-day complication rate of just 7.3%, with no bile duct…

Appendix, Gallbladder and Surgical Emergencies13 Aug 2025

Indocyanine Green Enhances Safety in Complex Liver Surgery

Anatomical segmentectomy of the liver using indocyanine green (ICG) fluorescence imaging significantly improves outcomes in cases of iatrogenic bile duct injury and recurrent cholangitis. A 46-year-old patient underwent surgical resection with ICG aiding in precise tissue identification and visualization, resulting in a successful procedure without…

Transl Gastroenterol Hepatol13 Aug 2025

Machine Learning Nomogram Predicts Laparoscopic Surgery Difficulty

A novel machine learning-based nomogram accurately predicts the surgical difficulty of laparoscopic cholecystectomy in gallstone patients. By analyzing 362 cases, the model integrated critical clinical and inflammatory indicators, achieving an impressive AUC of 0.863 in the validation set. This predictive capability enhances surgical planning and…

BJS Open13 Aug 2025

Preventing Pneumonia and Leaks Could Save Lives in Surgery

Postoperative complications significantly hinder recovery in oesophageal cancer surgeries. Pneumonia emerges as the top threat to survival, potentially leading to an 8.3% reduction in mortality if avoided. Anastomotic leaks drive reoperations and extended hospital stays, with impacts of 39.8% and 56.9%, respectively. Respiratory failure dominates…

Ann Surg12 Aug 2025

Tailored Antibiotic Prophylaxis Cuts Surgical Site Infections

An antimicrobial stewardship program tailored for pancreatic surgery significantly reduced surgical site infections (SSIs) linked to colonized bile. In a study of 1,638 pancreatoduodenectomies, the program cut overall SSI rates by 34% and superficial SSI rates by 59%. Importantly, the predictive value of intraoperative bile…

Ann Surg12 Aug 2025

Trisectionectomies Boost Survival in Perihilar Cholangiocarcinoma

Trisectionectomies (TS) dramatically enhance overall and disease-free survival for patients with Bismuth-Corlette type II and III perihilar cholangiocarcinoma, outperforming standard hemihepatectomies (EH). In a study of 443 patients, TS improved overall survival to 52.4 months compared to 31 months for EH. Although TS resulted in…

Ann Surg12 Aug 2025

New Model Predicts Recurrence Risk in Pancreatic Tumors

A predictive model effectively identifies patients with non-functioning pancreatic neuroendocrine tumors (NF-PanNETs) at high risk for early recurrence (ER). Developed from a cohort of 496 patients, the model leverages preoperative clinical, pathological, and imaging variables, achieving an AUC of 0.91 in training and 0.84 in…

World J Hepatol12 Aug 2025

New Insights Transforming Advanced Liver Cancer Treatment

With primary liver cancer often diagnosed too late for surgery, systemic treatments are becoming vital. The review highlights advances in molecular targeted therapies and immunotherapies, including cutting-edge combinations that suppress disease progression, extend survival, and enhance quality of life for patients. Challenges in implementation remain,…