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Best Papers in General Surgery
The five that matter, every day.
Endoscopic retrograde cholangiopancreatography (ERCP) outperformed percutaneous transhepatic biliary drainage (PTBD) in patients with severe acute cholangitis due to common bile duct stones. ERCP achieved definitive stone clearance in 92.1% of cases and enabled shorter hospital stays, with faster ambulation and reduced patient discomfort. Although both…
A structured Barrett's program has empowered early diagnosis and treatment of esophageal adenocarcinoma (EAC), revealing a 4.7% incidence rate of high-grade dysplasia (HGD) and EAC among patients. Over 9,400 patients were monitored, with a median follow-up of 4.4 years. Key risk factors for progression included…
Mini-laparoscopic cholecystectomy (mlc) using a 5 mm umbilical port significantly improves outcomes for obese patients with gallstones. The mlc group experienced no port-site hernias, shorter operative times (46 minutes vs. 52), less postoperative pain, and a quicker return to daily activities. Patient satisfaction surged while…
The NTAA prognostic model redefines outcomes for BCLC stage B hepatocellular carcinoma (HCC) patients undergoing transarterial chemoembolization (TACE). Analyzing over 2,500 patients, it identified tumor size, number, alpha-fetoprotein levels, and albumin-bilirubin grade as key survival predictors. Dividing patients into low, intermediate, and high-risk groups revealed…
In a multicenter study, endoscopic ultrasound-guided biliary drainage (EUS-BD) demonstrated superior efficacy to balloon enteroscopy-assisted ERCP (BEA-ERCP) for patients with surgically altered anatomy and unresectable malignant biliary obstruction. EUS-BD achieved a significantly higher technical success rate and shorter procedure times, while maintaining similar clinical success…
Robotic colorectal surgery (RCS) significantly accelerates bowel function recovery and reduces major complications compared to laparoscopic colorectal surgery (LCS). In a meta-analysis of 1,731 patients, RCS showed a 0.62-day improvement in bowel function, a 30% decrease in major complications, and a lower conversion rate to…
Liver resection demonstrates strong oncologic outcomes for colorectal liver metastases (CRLM), with a 90-day mortality rate below 5%. One-year overall survival (OS) rates exceed 85% for most patients, dropping to 78% for those with ten or more metastases. Five-year OS rates range from 28% to…
Once considered dangerously high-risk, ALPPS has evolved from >15% to
Enzymatic interactions from pancreatic juice cause critical vascular damage post-surgery, leading to severe hemorrhage. A study on porcine models reveals that trypsin and chymotrypsin significantly weaken arterial walls when mixed with intestinal fluids. However, administering nafamostat mesylate, a protease inhibitor, effectively mitigates this histopathologic damage.…
Surgical patients in Addis Ababa face median hospital stays of six days, primarily due to comorbidities, infections, and functional impairments. Key predictors include weight loss and dietary changes, all stressing the need for targeted preoperative assessments. A proactive approach could enhance recovery and minimize healthcare…
