Newsletter
Best Papers in General Surgery
The five that matter, every day.
Colorectal cancer (CRC) is increasingly prevalent in Ghana, often diagnosed at younger ages and later stages, which leads to poorer survival rates. Key challenges identified include limited healthcare resources, inadequate screening, and sociocultural barriers that affect treatment access. The study emphasizes the need for enhanced…
The developed AI-assisted system significantly improves the detection and localization of colorectal polyps during colonoscopy. Out of five CNN models tested, EfficientNetV2 excelled, achieving an accuracy of 93.3% and a specificity of 94.6% on the test set. The system's performance metrics, including a high AUC…
Anastomotic leaks (AL) after esophagectomy pose significant risks, leading to complications and prolonged recovery. Recent reviews highlight three key management approaches: conservative measures like nutritional support, endoscopic interventions that show promising success rates, and surgical options for severe cases. Innovative hybrid techniques are emerging, while…
The research highlights keratin 5 (KRT5) and versican (VCAN) as effective biomarkers for early detection and clinical monitoring of pancreatic ductal adenocarcinoma (PDAC). In a multicenter validation study with over 1,000 plasma samples, a combined diagnostic model featuring KRT5, VCAN, and the existing CA 19-9…
An innovative MRI-based fusion model effectively predicts perineural invasion (PNI) status in intrahepatic cholangiocarcinoma (ICC) patients. The model, incorporating deep learning, radiomics, and clinical features, was developed from a study involving 192 patients. In the training phase, it achieved an AUC of 0.905 and 82.3%…
Evaluation of total metastases volume (TMV) and relative volume reduction (RVR) reveals their superior predictive ability over established clinical risk scores (CRS) for colorectal liver metastases post-neoadjuvant chemotherapy. Patients with TMV below 29.5 ml before and 7.5 ml after therapy had significantly longer progression-free survival…
A predictive model utilizing endoscopic ultrasound (EUS) parameters has been developed, demonstrating significant efficacy in predicting pathologic complete response (PCR) in esophageal cancer patients undergoing neoadjuvant immunotherapy combined with chemotherapy. Key predictors identified were treatment regimen, negative biopsy findings, RECIST assessment, EUS responsiveness, and downstaging.…
In patients undergoing Roux-en-Y reconstruction for gastric cancer, ω-3 fish oil fat emulsion significantly decreased the incidence of delayed gastric emptying (DGE) from 15.5% to 4.3%, highlighting its protective role. The intervention group also experienced a shorter median hospital stay of 10 days compared to…
A nationwide study in Denmark reveals that patients with alcohol-related cirrhosis have a substantially elevated risk of requiring surgery compared to matched individuals from the general population. With a 1-year surgery risk of 42.6% for these patients, versus 13.4% for comparators, the incidence rate ratio…
A meta-analysis revealed a 11.73% rate of unplanned readmissions within 31 days post-colorectal cancer surgery. Significant risk factors include age, postoperative complications, advanced tumor stage, rectal tumor site, stoma creation, complicated diabetes, Charlson comorbidity index, blood transfusions, longer hospital stays, and surgical approach. Additionally, being…
