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Best Papers in General Surgery
The five that matter, every day.
Laparoscopic cholecystectomy shows superior clinical efficacy compared to non-invasive gallstone dissolution, enhancing patient quality of life. In a study of 86 cholelithiasis patients, surgical intervention resulted in a higher effective rate, faster symptom relief, and shorter hospital stays, despite increased costs. Additionally, the surgical group…
A study of 304 rectal cancer surgery patients revealed that moderate or severe anemia and non-use of indocyanine green fluorescence imaging (ICG-FI) are significant independent risk factors for anastomotic leakage. Preoperative anemia correction and routine ICG-FI application may reduce this risk. The analysis calculated an…
A new study identifies a preoperative carcinoembryonic antigen (CEA) cutoff of 2.8 ng/ml as significant for predicting 5-year survival in rectal cancer patients. Analysis of 316 individuals revealed that higher CEA levels correlate with poor overall survival. The presence of lymphovascular and perineural invasions also…
Improved outcomes for patients with initially unresectable hepatocellular carcinoma are linked to the depth of radiographic response after systemic therapy prior to hepatectomy. In a study of 81 patients, radiographic response emerged as an independent prognostic factor for both recurrence-free and overall survival. Notably, achieving…
Neoadjuvant therapy (NAT) with FOLFIRINOX significantly enhances resectability and overall survival (OS) in patients with locally advanced pancreatic cancer (LAPC). This umbrella review of nine systematic reviews highlights that FOLFIRINOX leads to higher R0 resection rates compared to gemcitabine/nab-paclitaxel, with improved OS. Furthermore, surgical resection…
A novel nomogram has been developed to accurately predict late extraluminal postpancreatectomy hemorrhage (lepph) in patients with postoperative pancreatic fistula following pancreaticoduodenectomy. Utilizing a combination of key independent risk factors such as dorsal fluid accumulation and positive cultures in drainage fluid, the model demonstrated high…
A novel preoperative risk score predicts 90-day mortality after major liver resection, identifying five key risk factors: age ≥ 65 years, type 2 diabetes, a diagnosis of primary liver cancer, ASA ≥3, and extended hemihepatectomy. In a cohort of 513 patients, the 90-day mortality rate…
A retrospective analysis of 2,976 patients with solitary colorectal lung metastases revealed that surgical resection significantly enhances survival rates. Specifically, patients who underwent surgery had a five-year survival rate of 42.7%, compared to 29.7% for radiation therapy and 23.9% for conservative management. Multivariate analysis confirmed…
A significant 48.4% of patients undergoing salvage local resection (SLR) for incompletely resected rectal neuroendocrine tumors (r-NETs) had residual tumors. Rates varied by resection method: 70% for cold forceps polypectomy, 41.7% for conventional polypectomy/endoscopic mucosal resection, and 0% for modified techniques. Multivariate analysis indicated that…
A study found that enhanced recovery after surgery (ERAS) nursing interventions significantly improved postoperative outcomes for patients undergoing endoscopic resection of early gastrointestinal tumors. Compared to conventional care, patients in the ERAS group experienced lower complication rates, shorter hospital stays (4.8 vs. 6.3 days), and…
