Newsletter
Best Papers in General Surgery
The five that matter, every day.
A comparative analysis of two surgical approaches for deep perianal abscess found that the intersphincteric approach with internal incision and counter-drainage achieved a cure rate of 91.2%, significantly higher than the 76.2% cure rate for traditional incision-drainage. While the intersphincteric method required more time during…
A secondary analysis of the ChoCO-W cohort study indicates that COVID-19 infection substantially heightens the mortality risk for patients with acute cholecystitis. Among 2,546 cases evaluated, those infected with COVID-19 had a fivefold increased risk of death. Other independent factors included postoperative complications and type…
In a study involving 187 patients with peptic ulcer perforation, the red cell distribution width-to-albumin ratio (RAR) was found to be a strong prognostic marker for predicting major postoperative complications and 30-day mortality. The analysis revealed RAR, alongside age and surgical delay, as independent predictors…
A systematic review involving 14,555 participants reveals that side-to-side anastomosis (SSA) is more effective than end-to-side anastomosis (ESA) in reducing postoperative anastomotic bleeding during laparoscopic right hemicolectomy for cancer patients. No significant differences were found in overall anastomotic complications, though SSA was advantageous in minimizing…
A systematic review and meta-analysis comparing liver resection (LR) and radiofrequency ablation (RFA) for solitary hepatocellular carcinoma (HCC) ≤3 cm highlights that LR offers superior overall survival, disease-free survival, and recurrence-free survival compared to RFA, particularly for lesions ≤2 cm. While no significant differences were…
Recent findings reveal that external-beam radiation therapy (EBRT) significantly enhances patient outcomes in hepatocellular carcinoma, addressing critical care gaps. Randomized trials show that EBRT boosts overall survival and recurrence-free survival compared to conventional treatments, particularly when combined with sorafenib. Additionally, it improves the quality of…
Findings indicate that cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) and intraoperative radiation therapy (IORT) significantly improves overall survival (63 months) and disease-free survival (87 months) for gastric cancer patients. Over one-third of participants experienced no postoperative complications, while those who did faced a…
Colorectal cancer mortality in underserved regions of Washington shows alarming trends, with non-white patients dying 8 years earlier than their counterparts. A significant 40% drop in screenings was noted post-pandemic. Targeted outreach initiatives, including presence at local health fairs and farmers' markets, aim to engage…
A machine learning-based model has been developed to predict postoperative recurrence in patients with duodenal adenocarcinoma, utilizing data from 1,830 patients who underwent radical surgery. Among 100 predictive models tested, the penalized regression + accelerated oblique random survival forest model (pam) delivered the highest performance…
A systematic review and meta-analysis revealed five significant risk factors linked to failure in achieving textbook outcomes following pancreatoduodenectomy. Key contributors include preoperative biliary drainage, smaller tumor size, soft pancreatic texture, small pancreatic duct diameter, and increased intraoperative blood loss. These findings, synthesized from ten…
