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Best Papers in General Surgery
The five that matter, every day.
A novel nomogram, based on liver stiffness (ls) via 2D-sheared wave elastography and spleen area (spa), was developed to predict posthepatectomy liver failure (PHLF) in hepatocellular carcinoma patients. Analysis of 562 patients demonstrated superior diagnostic performance compared to conventional models, such as the MELD and…
A retrospective cohort study analyzing 1,317 emergency hiatal hernia repairs revealed that fundoplication significantly reduced 30-day complication (odds ratio [OR] 0.53, p < 0.001) and mortality rates (OR 0.55, p = 0.033) compared to gastric fixation. No significant differences were found regarding 30-day readmission (OR…
Preoperative music significantly decreased hemodynamic instability and anxiety among women undergoing elective non-cardiac surgery. In a study involving 164 participants, those in the music intervention group exhibited lower mean arterial pressure fluctuations and heart rate instability compared to the control group. Furthermore, the State-Trait Anxiety…
A retrospective study analyzed 2,155 patients admitted after the February 2023 Kahramanmaraş earthquake. Falls accounted for 57.2% of injuries, with significant occurrences of rhabdomyolysis (20.6%) and fractures (11.1% upper, 21.3% lower extremities). The orthopedics department performed the most surgical interventions, revealing a critical need for…
The study developed a prognostic nomogram for gastric cancer patients post-neoadjuvant chemotherapy and radical surgery, revealing promising results. The median progression-free survival was 43.8 months, and overall survival reached 61.2 months. The nomogram demonstrated excellent discrimination with a c-index of 0.689 and area under the…
Elevated interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels in serum and drainage fluid indicate infectious complications following minimally invasive gastric cancer surgery. Among 205 patients, pod 1 serum IL-6 levels above 47 pg/ml exhibited 74.1% sensitivity, while drainage fluid IL-6 levels over 14,750 pg/ml…
In a systematic review of six randomized controlled trials involving 736 patients, the anterior approach with or without liver hanging maneuver demonstrated significant survival benefits over conventional techniques. Overall and disease-free survival rates improved markedly (HR: 0.65; p < 0.0001). Although associated with longer surgery…
Diagnostic accuracy for appendicitis improves beyond 90% when utilizing Alvarado criteria, ultrasound, and CRP together. Individual sensitivities showed Alvarado at 75.2% compared to ultrasound and CRP, which were higher. Analyses demonstrated that combinations, particularly Alvarado with CRP, outperformed others, indicating a need for a more…
Significant causal effects of genetically predicted cholelithiasis, cholecystitis, and cholecystectomy on gastroesophageal reflux disease (GERD) were identified, with odds ratios of 1.04, 1.06, and 2.56, respectively. Additionally, the study confirmed a bidirectional relationship, where GERD also influences the likelihood of developing cholelithiasis and cholecystitis. Mediation…
The study identified several key prognostic factors impacting unresectable recurrence-free survival (urfs) in colorectal liver-only metastasis patients. Significant predictors included KRAS G12D mutation positivity (HR: 7.69), RYR2 mutation positivity (HR: 4.03), KRAS G12S mutation positivity (HR: 3.96), CA19-9 > 37 U/ml prior to hepatectomy (HR:…
