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Best Papers in General Surgery
The five that matter, every day.
In a randomized controlled trial involving 363 patients with large nonpedunculated colorectal polyps, cold endoscopic mucosal resection (EMR) demonstrated a significantly lower rate of major adverse events (1.0%) compared to hot EMR (7.9%, p = .001). While cold resection did result in a higher rate…
Transmucosal internal sphincterotomy demonstrates significant advantages in treating fissure in ano compared to traditional methods. The procedure had a median operative time of 7 minutes, yielding a mere 2.5% infection rate and 3% transient incontinence rate. Postoperative pain was notably lower, with a majority of…
With a remarkable 0% conversion and mortality rate, the "easy first" technique for laparoscopic hepatic caudate lobectomy has shown promise in safety and effectiveness. By employing sextet strategies—meticulous planning, optimal trocar placement, and efficient team positioning—clinicians can tackle the complexities of the caudate lobe. The…
A retrospective analysis of 25,848 pancreaticoduodenectomy patients revealed that 10.5% had preoperative hypoalbuminemia, which significantly correlated with increased 30-day complications. Specifically, hypoalbuminemic patients faced higher risks for serious complications (OR 1.80) independent of other comorbidities but did not have increased mortality risk (OR 1.37). The…
A novel attention-based convolution transpositional interfusion network (ACTIN) has shown promising results for drug discovery with limited data. Utilizing just 393 training instances, ACTIN achieved state-of-the-art performance by leveraging graph convolution and transformer mechanisms to analyze drug and transcriptome data. It identifies pharmacophores that may…
Findings indicate that the same-day discharge (SDD) protocol for bariatric surgery shows a favorable safety profile, achieving a 30% success rate for SDD sleeve gastrectomy and a 6% rate for SDD Roux-en-Y gastric bypass. The study recorded 811 sleeve gastrectomies and 325 Roux-en-Y procedures, highlighting…
The two-parts wrapping technique significantly reduces postoperative pancreatic fistula (POPF) and postpancreatectomy hemorrhage (PPH) in laparoscopic pancreaticoduodenectomy (LPD). Analyzing data from 172 patients, researchers found lower rates of overall and severe complications, particularly in patients with soft pancreatic textures and smaller duct diameters. Notably, the…
Comparative analysis revealed that single anastomosis sleeve ileal (SASI) bypass leads to greater weight loss than sleeve gastrectomy (SG) with a mean difference of 11.32 kg, and improves metabolic parameters, including type 2 diabetes mellitus (RR=1.35), dyslipidemia (RR=1.41), and obstructive sleep apnea (RR=1.50). No significant…
Enhanced overall survival (27.0 months) and progression-free survival (8.0 months) were observed in the HAIC-len-p group compared to the len-p alone group (9.0 months and 3.0 months, respectively, p
A study involving 604 low rectal cancer patients revealed a 71.9% successful sphincter-preserving resection (SSPR) rate, with hospital rates ranging from 37.7% to 94.4%. Researchers developed seven AI algorithms, including logistic regression and light gradient boosting, achieving excellent discrimination for predicting SSPR, with Area Under…
