Category: General Surgery

Impact of Surgeon Gender on Postoperative Mortality

Patients treated by female surgeons experienced lower postoperative mortality compared to those treated by male surgeons, especially for elective surgeries. No significant differences were found in readmission or complication rates. This meta-analysis of 15 retrospective cohort studies involving over 5 million participants provides moderate certainty evidence that surgeon gender may influence patient outcomes post-surgery. Journal […]

Risk Factors for Anastomotic Leak After Esophagectomy

An analysis of 4,331 patients undergoing esophagectomy revealed smoking, frailty index, white blood cell count, mckeown esophagectomy, and platelet counts were associated with anastomotic leak. Results showed increased odds of leak with smoking, frailty index scores of 1 or 2, and specific surgical techniques, while higher platelet counts were slightly protective. These findings offer crucial […]

Comparison of Intestinal Perfusion Using ICG and MB Imaging

Real-time assessment of bowel perfusion using methylene blue and indocyanine green was successful in a porcine model, with MB showing a stronger correlation with local lactate levels compared to ICG. This study demonstrates the potential utility of MB as a viable alternative for assessing intestinal perfusion alongside ICG. Further research is needed to translate these […]

Effects of Esophagectomy on Weight Loss and Glycolipid Profile in Type 2 Diabetes Patients

Esophagectomy induces weight loss and improves glucose and lipid metabolism in type 2 diabetes patients. Both diabetic and non-diabetic groups experience similar reductions in weight and BMI post-surgery. Fasting plasma glucose levels decrease significantly in the diabetic group, while HDL levels increase in the non-diabetic group. TG, LDL, and TC levels decrease significantly in both […]

Effectiveness of Near-Infrared Indocyanine Green Imaging in Laparoscopic Rectal Cancer Surgery

Utilizing the NIR-ICG imaging system during laparoscopic rectal cancer surgery can potentially reduce the incidence of anastomotic leakage (AL), a serious complication. The study protocol, a randomized controlled trial, aims to evaluate AL rates in patients receiving NIR-ICG during total mesorectal excision compared to conventional surgery. Expected outcomes and sample sizes have been carefully considered, […]

Enhanced Disease-Free Survival in Pancreatic Cancer Patients with Neoadjuvant Chemotherapy and Vascular Resection

Neoadjuvant chemotherapy before pancreaticoduodenectomy with vascular resection led to improved disease-free survival in pancreatic cancer patients. Patients who received neoadjuvant chemotherapy had more favorable pathological outcomes, decreased vascular invasion, and completed chemotherapy more often. The neoadjuvant chemotherapy group exhibited a significant increase in disease-free survival compared to those who underwent upfront surgery, highlighting the advantages […]

Impact of Tumor Marker Regression Load Score on Prognosis of Gastric Cancer Patients

Novel findings suggest that the Tumor Marker Regression Load Score (TMRLS) is a significant independent prognostic factor for gastric cancer patients undergoing neoadjuvant chemotherapy and radical surgery. Patients with high TMRLS who received postoperative adjuvant chemotherapy showed better survival outcomes. The TMRLS-based nomogram demonstrated superior predictive performance compared to traditional staging methods. These results provide […]

Impact of Disease Phenotype and Biologic Therapy on Re-resection Rates in Crohn’s Disease

Re-resection rates in Crohn’s disease patients are significantly influenced by disease activity and stoma reversals. The study reveals that early initiation of biologic therapy after primary resection can reduce the risk of re-resection for specific disease phenotypes. Factors such as disease location, behavior, smoking, and perianal disease also play a role in re-resection. These findings […]

Impact of Postoperative Complications on Prognosis in Patients with Hepatocellular Carcinoma

Postoperative complications significantly impact patient outcomes in hepatocellular carcinoma. Patients with moderate/severe complications had worse recurrence-free survival compared to those with no/mild complications. Notably, low and medium alpha-feto protein-tumor burden score patients with complications had higher recurrence risks, whereas complications did not affect high score patients. These findings highlight the importance of reducing postoperative complications […]

Long-term Outcomes of Primary Closure in Pilonidal Sinus Disease

Comparing two surgical techniques for pilonidal sinus disease, midline closure without skin sutures showed significant advantages over excision and primary closure. Patients in the midline closure group experienced shorter surgical procedures, hospital stays, and time to return to work. Additionally, they had lower complication rates and no recurrence during a five-year follow-up period. This technique […]