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General Surgery

Best Papers in General Surgery

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HPB (Oxford)7 Jun 2024

Artificial intelligence predicts non-transplantable recurrence in hepatocellular carcinoma

Artificial intelligence models accurately predicted non-transplantable recurrence in hepatocellular carcinoma patients post-hepatic resection. An ensemble AI model showed high accuracy (AUC 0.751-0.858) with incorporation of postoperative factors. Radiologic tumor burden and microvascular invasion were key predictors. Patients with predicted recurrence had lower survival rates, highlighting…

World J Clin Cases7 Jun 2024

Prognostic Model for Unresectable Gastric Cancer Liver Metastases

Study establishes a reliable nomogram model with five independent risk factors for gastric cancer liver metastases. The model accurately predicts patient prognosis, showing promising predictive accuracy and clinical benefit for outcome evaluation. Results demonstrate high area under the curve values at 1, 3, and 5…

Endocrine Surgery7 Jun 2024

Reduced postoperative sore throat with combined budesonide and dexamethasone

Preoperative inhaled budesonide combined with intravenous dexamethasone significantly decreased postoperative sore throat (post) incidence and severity at 6, 12, and 24 hours in patients undergoing thyroidectomy. Additionally, this combination resulted in lower postoperative coughing rates at 24 hours compared to intravenous dexamethasone alone. Hoarseness outcomes…

J Gastrointest Surg6 Jun 2024

Management and Prognosis of Ruptured Hepatocellular Carcinoma

Spontaneous rupture of hepatocellular carcinoma (RHCC) presents a life-threatening complication in 3-15% of patients with HCC. Recent studies show improved survival benefits with transcatheter arterial embolization followed by elective hepatectomy. Despite poor prognosis, active surveillance and multidisciplinary management strategies can enhance short- and long-term outcomes.…

Upper Gastrointestinal Tract6 Jun 2024

Indocyanine Green Fluorescence for Lymph Node Metastasis in Gastric Cancer

Indocyanine Green (ICG) fluorescence in laparoscopic subtotal gastrectomy for gastric cancer showed a sensitivity of 75.86% in detecting metastatic lymph nodes and 90.7% in identifying them. ICG-guided lymphadenectomy revealed higher fluorescent lymph node numbers in patients with metastases. The method offers high negative predictive value…

J Surg Res6 Jun 2024

Factors associated with loss to follow-up in surgical trials

Loss to follow-up (LTFU) is uncommon in surgical randomized controlled trials. Characteristics associated with reduced LTFU include standard-of-care outcome assessments, surgery for transplantation or cancer. Increased LTFU risk is seen in trials with patient-reported outcomes and longer follow-up periods. Understanding these factors can help investigators…

J Surg Res6 Jun 2024

Sex Differences in Weight Loss and Complications Post Bariatric Surgery

Male patients had slightly greater weight loss and higher complication rates compared to females following bariatric surgery. However, these differences were not clinically significant. Providers should consider referring males earlier for surgery given their higher comorbidity rates. This study highlights the need to assess sex…

J Crohns Colitis6 Jun 2024

Filgotinib 200 mg Shows Efficacy in Perianal Fistulising Crohn’s Disease

Filgotinib 200 mg demonstrated efficacy in treating perianal fistulising Crohn's disease, with a higher proportion of participants achieving a combined fistula response compared to lower doses and placebo. Serious adverse events were more frequent with the 200 mg dose, but no treatment-related serious adverse events…