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General Surgery

Best Papers in General Surgery

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J Crohns Colitis6 Jun 2024

High Rates of Colitis-Associated Post-Colonoscopy Colorectal Cancers

Analysis reveals 61% of inflammatory bowel disease-related colorectal cancers were post-colonoscopy, often due to delays in surveillance and missed lesions in areas of inflammation. Proactive strategies are needed to reduce endoscopic burden and improve surveillance adherence, as traditional methods show limitations in detecting aggressive cancer…

Hepatobiliary Pancreat Dis Int6 Jun 2024

Development of Gallstone Recurrence Prediction Model

A nomogram model was developed to predict gallstone recurrence after gallbladder-preserving surgery based on identified risk factors. Factors such as gallstone duration, symptoms, number of stones, cholecystitis history, and diet were significant predictors. The nomogram showed good predictive value (c-index = 0.692). Clinicians can utilize…

Eur Surg Res6 Jun 2024

Improved Surgical Outcomes with Thoracic Duct Visualization

Patent blue injection enhances intraoperative thoracic duct visualization during esophagectomy. In a pilot trial, the duct was visualized in 60% of patients, leading to significantly shorter operative times, fewer complications, and shorter hospital stays compared to controls. Although chyle leak rates did not significantly differ,…

Ann Surg Oncol5 Jun 2024

Improved Survival Prediction in Intrahepatic Cholangiocarcinoma

Preoperative CT radiomics of intrahepatic cholangiocarcinoma and peritumoral tissue enhances survival prediction. Combined with clinical data, the radiomic model achieves equivalent prognostic estimates compared to postoperative pathology. In a study of 215 patients, the addition of radiomic features led to a significant improvement in overall…

World J Gastroenterol5 Jun 2024

Combination Therapy Improves Survival in Early-Onset Pancreatic Cancer

Study on non-metastatic early-onset pancreatic cancer patients showed postoperative survival improvement with adjuvant therapy. Surgery followed by neoadjuvant and adjuvant therapy recommended for locally advanced cases. 1-year, 2-year, and 3-year overall survival rates were 84.3%, 51.5%, and 27.6% respectively. Findings suggest a positive impact of…

Upper Gastrointestinal Tract5 Jun 2024

Anti-reflux mucosectomy reduces reflux symptoms in GERD patients

Anti-reflux mucosectomy (ARMS) effectively reduced reflux episodes and acid exposure in GERD patients unresponsive to PPI treatment. ARMS also decreased transient lower esophageal sphincter relaxations (TLESRs) and reflux symptoms without impacting esophageal distensibility. These findings support ARMS as a viable option for managing PPI-refractory GERD,…

J Surg Oncol5 Jun 2024

Adjuvant Chemotherapy Benefits Post-Pancreaticoduodenectomy

Adjuvant therapy following pancreaticoduodenectomy for pancreatic adenocarcinoma shows improved overall survival. Patients who responded favorably to neoadjuvant therapy may not benefit from additional adjuvant treatment. Downstaging after neoadjuvant therapy is a key factor in determining the efficacy of adjuvant therapy post-surgery. The study highlights the…

J Surg Oncol5 Jun 2024

Reduced Hospital Readmission and Mortality with Early Primary Care Follow-up

Early primary care physician follow-up after gastrointestinal cancer surgery significantly lowered 90-day readmission rates by 38% and decreased mortality risk by 50%. Patients with post-discharge PCP visits had lower healthcare costs and better outcomes. Integrating in-hospital and community-based care is crucial for improving patient results…

J Hepatobiliary Pancreat Sci5 Jun 2024

Improved Recurrence Prevention with Anatomical Liver Resection for Hepatocellular Carcinoma

Anatomical liver resection (AR) significantly reduces local and early recurrence rates compared to nonanatomical liver resection (NR) in patients with solitary hepatocellular carcinoma (HCC) ≤5cm. AR group exhibited lower recurrence rates, improved overall survival, and fewer instances of early recurrence. NR was identified as an…