Newsletter
Best Papers in General Surgery
The five that matter, every day.
Study investigates the combined tumor markers CEA and CA19-9 in colon cancer patients. 531 patients underwent curative resection, with higher preoperative and postoperative tumor marker levels associated with lower recurrence-free and overall survival rates. Patients with elevated postoperative tumor markers had increased risk of recurrence…
Perineural invasion is an independent poor prognostic factor in stage III colon cancer but does not predict outcomes in node-negative disease. Adjuvant chemotherapy benefits patients with node-positive but not those with node-negative disease when perineural invasion is present. Higher recurrence odds are seen only in…
Delayed gastric emptying (DGE) after laparoscopic pancreaticoduodenectomy (LPD) was studied in 827 patients. Preoperative biliary drainage, blood loss, and major complications were significant risk factors for DGE. Higher BMI, soft pancreatic texture, and perioperative transfusion increased the risk of secondary DGE. Identifying at-risk patients can…
3D-printed models reduce intraoperative blood loss and postoperative complications, particularly bile leakage, in complex hepatobiliary laparoscopic surgeries. Patients guided by 3D models had significantly lower comprehensive complication index scores compared to the control group. Multivariable analysis confirmed 3D models as independent protective factors against complications.…
Development of a risk calculator using 12 variables showed excellent predictive ability for mortality among unseen emergency general surgery patients at the time of interhospital transfer. With a mortality rate of 6.0%, the model demonstrated high performance metrics with an area under the receiver operating…
High county-level provider density is linked to lower colorectal cancer-related mortality rates, independent of social vulnerability index. Efforts to increase access to health care providers could enhance health care equity and long-term cancer outcomes. Low provider density areas exhibited higher crude mortality rates compared to…
In a single-center experience, 127 patients underwent palliative surgery for advanced cancer, with a high symptom resolution rate of 89%. Complication and mortality rates were 19.7% and 6%, respectively. Successful symptom palliation significantly correlated with the potential to resume systemic chemotherapy, impacting overall survival. Palliative…
Increasing cases of non-hepatitis B and non-hepatitis C hepatocellular carcinoma (NBNC-HCC) prompt a comparison with hepatitis virus-associated HCC. A retrospective study of 1321 liver resections showed comparable operative outcomes and long-term survival between matched NBNC-HCC and HV-HCC groups. Independent prognostic factors for overall survival were…
Preoperative aerobic fitness, along with other factors like age, sex, and tumor location, can predict postoperative complications and physical recovery time in colorectal cancer surgery patients. The developed models show moderate discrimination and good calibration, offering a promising tool for personalized risk assessment and targeted…
During a study of 1056 patients undergoing laparoscopic hepatectomy, 75% achieved a textbook outcome (TO). Factors like age, ASA classification, and tumor characteristics influenced TO attainment. Notably, patients reaching TO showed improved survival rates, suggesting its importance in precision surgery and patient outcomes.
