Newsletter
Best Papers in General Surgery
The five that matter, every day.
Researchers developed prediction models using preoperative data to assess short-term mortality risk following colorectal cancer surgery. The models showed good discrimination and calibration, with an area under the receiver operating characteristic curve of 0.88, 0.878, and 0.861 for 30-day, 90-day, and 1-year mortality, respectively. Subgroup…
Expert-informed prediction models and machine learning models both showed similar performance in predicting postoperative overall morbidity in liver surgery patients, with high variability and over/underprediction. There was no improvement in performance for major liver surgery patients, indicating that machine learning may not have clinical relevance…
Findings from a study on 105 patients who underwent Whipple's procedure for pancreatic cancer revealed that inferior pancreatic duct topography was linked to higher rates of metastatic spread and tumor recurrence, as well as reduced overall and recurrence-free survival. Conversely, posterior pancreatic duct topography was…
Survival and quality of life outcomes in patients with uveal melanoma liver metastases treated with isolated hepatic perfusion were evaluated in a Phase III randomized controlled trial. Isolated hepatic perfusion led to significantly longer progression-free survival compared to standard care, but no significant difference in…
Patients with oesophageal squamous cell carcinoma who underwent active surveillance after chemoradiotherapy showed comparable overall survival but better progression-free survival than those who had planned surgery. The two groups had similar overall recurrence rates, with locoregional recurrence more common in the active surveillance group and…
Patients with behavioral health disorders (BHD) had lower rates of resection and higher odds of complications, longer hospital stays, readmission, and higher in-hospital expenditures. They were also less likely to achieve a postoperative textbook outcome and had worse long-term survival. Initiatives targeting BHD are crucial…
According to the study, laparoscopic gastric ischemic preconditioning (LGIP) may decrease the rate and severity of anastomotic strictures following esophagectomy. Of the patients who underwent LGIP, only 7.1% developed anastomotic strictures compared to 19.9% in the control group. While controlling for confounders, the difference was…
CRC incidence is significantly higher in patients with high-risk adenomas (HRAs) diagnosed at colonoscopy, with a 1.53-fold increase in risk. However, patients with only distal pedunculated polyps without high-grade dysplasia do not have an increased CRC risk. The presence of certain risk factors explains most…
Multidisciplinary team management in retroperitoneal liposarcoma treatment led to higher overall survival rates at 1, 3, and 5 years, improved diagnostic consistency, reduced perioperative mortality and postoperative complications, and enhanced disease awareness and postoperative compliance. The intervention showed significant benefits in clinical outcomes and diagnostic…
Quality of life trajectories after pelvic exenteration diverge into distinct classes, with most patients experiencing optimal outcomes. Two classes were identified for physical scores and three for mental and functional scores, with higher overall survival probabilities in the optimal trajectory class. Age, repeat surgery, neoadjuvant…
