Gastric neuroendocrine neoplasms are on the rise, necessitating improved prognostic tools for better surgical outcomes. Incidence increased 16-fold over 46 years, from 0.435 to 7.033 per 1,000,000 people. A newly developed nomogram showed superior predictive accuracy (c-index of 0.86) compared to the AJCC staging system. Understanding these risk factors—age, sex, tumor characteristics, and surgical intervention—can […]
Category: Upper Gastrointestinal Tract
Spleen Preservation Cuts Complications in Total Gastrectomy
Spleen-preserving gastrectomy lowers complication rates in proximal gastric cancer. Reduced pancreatic fistula risk (RR 0.30; p < 0.000001) Less blood loss (MD -172.47; p = 0.012396) This approach supports safer patient outcomes when oncologic safety is prioritized. Lower risk of anastomotic leak (RR 0.51; p = 0.006769) and intra-abdominal abscess (RR 0.40; p = 0.000160) […]
Survival Gains with FLOT in cT2cN0 Esophageal Cancer
FLOT chemotherapy significantly improves survival in patients with cT2cN0 adenocarcinoma of the esophagus compared to chemoradiotherapy. Mean survival: 100.8 months for FLOT vs. 74.6 months for CROSS (p = 0.028). Three-year survival rates: 87% for FLOT vs. 59% for CROSS. Surgeons should prioritize FLOT treatment in multimodal approaches for these patients to enhance outcomes. 23.3% […]
Robotic Gastrectomy Enhances Outcomes in Locally Advanced Cancer
Robotic gastrectomy significantly improves surgical and survival outcomes for patients with locally advanced gastric cancer. 47.6% of robotic gastrectomy patients achieved textbook oncological outcomes, compared to 32.5% for laparoscopic. No severe complications in 98.4% of robotic cases vs. 89.7% for laparoscopic (p=0.006). 3-year overall survival rates were 86.2% for those achieving outcomes versus 65.5% for […]
Predicting outcomes in oesophagogastric junction cancer
Unexpected horizontal tumor spread significantly impacts outcomes for patients with oesophagogastric junction (OGJ) cancer, influencing surgical decisions. Patients with long pathological margins (δpm > 8mm) and long distal margins (δdm > 3mm) faced worse recurrence-free survival (RFS) and overall survival (OS). The long margin group was identified as an independent risk factor for poor RFS […]
Preoperative Nutrition Status Affects Gastric Cancer Outcomes
Poor nutritional status pre-surgery leads to worse outcomes in gastric cancer patients undergoing radical gastrectomy. Low preoperative prognostic nutritional index (PNI) increases overall survival risk by 34% and disease-free survival risk by 22%. Patients with lower PNI and higher nutritional risk scores face 6.31 days more in the hospital and higher costs after complications. Screening […]
Thumbtack Needle Helps GI Recovery Post-Gastrectomy
This study shows that thumbtack needle therapy can accelerate gastrointestinal recovery in gastric cancer surgery patients. Patients receiving therapy had bowel sound recovery 4 hours faster than the control group. The intervention did not increase complications and was deemed safe. Surgeons can consider incorporating thumbtack needle therapy to enhance recovery protocols after laparoscopic radical gastrectomy. […]
Prolonged Ventilation Cuts Esophageal Leak Rates
Prolonging mechanical ventilation after minimally invasive esophagectomy significantly reduces anastomotic leak rates. Patients on prolonged mechanical ventilation (≥24 hours) had a lower leak rate (8.08%) compared to those with non-prolonged ventilation (23.47%). The difference in leak rates remained significant even after matching for other variables (7.88% vs 24.71%). This suggests extended ventilation may improve postoperative […]
Improved Prognostic Tools for Gastric Cancer After Surgery
Linking new lymph node staging methods to better survival outcomes in gastric cancer enhances surgical decision-making. The lymph node ratio (lnr) and log odds of positive nodes (lodds) significantly predict survival alongside traditional pN staging (p=0.002 and p=0.036). In cases with fewer than 15 lymph nodes dissected, only lnr remains prognostic (p=0.037). Using lnr and […]
Effective Surgery for GERD-Related Chronic Cough
A study confirms transoral endoscopic fundoplication (TIF) is effective in treating GERD patients with chronic cough. 177 patients showed a significant reduction in cough severity: median reflux symptom index (RSI) score dropped from 18 to 5 (p < 0.0001). 83% of patients normalized their cough scores, and 83% successfully reduced or stopped proton pump inhibitors. […]
