Category: Upper Gastrointestinal Tract

Risk Factors for Perforation in Gastric Endoscopic Submucosal Dissection

Study identified risk factors for intraoperative and delayed perforations in gastric endoscopic submucosal dissection for early gastric cancer. Intraoperative perforation occurred in 2.2% of patients, necessitating emergency surgery in 0.04% of cases, while delayed perforation occurred in 0.4% of patients, with emergency surgery required in 0.12% of cases. Factors like location in upper or middle […]

NICE Guidelines Emphasize Barrett’s Oesophagus Surveillance

NICE guidance emphasizes the importance of monitoring Barrett’s oesophagus due to its link to oesophageal adenocarcinoma. Risk factors include acid reflux symptoms, obesity, male gender, smoking, and family history. Surveillance allows for early detection and intervention, leading to excellent prognoses for dysplasia and stage I cancer. Endoscopic techniques are crucial for accurate staging and eradication […]

Resection Improves Survival in Patients with Local Recurrence of Esophageal Cancer

Patients with local recurrence of esophageal cancer following Ivor-Lewis esophagectomy have a significantly decreased overall survival. A retrospective study at a high-volume center showed that patients who underwent resection had better survival outcomes compared to those who did not. Chemoradiotherapy also showed promise in selected cases. Best supportive care was associated with shorter survival. These […]

Impact of Sarcopenia on Perioperative Outcomes and Survival After Esophagectomy for Cancer

Patients with preoperative sarcopenia, identified using skeletal muscle index, had higher rates of major complications, including cardiac arrhythmia and mortality. They also had significantly lower overall survival and disease-free survival compared to non-sarcopenic patients. Sarcopenia was found to be an independent risk factor for lower survival on multivariate analysis. Sarcopenia is associated with increased risks […]

Effective guidance for safe laparoscopic total gastrectomy in remnant gastric cancer using indocyanine green fluorescence imaging

Researchers successfully performed laparoscopic total gastrectomy in two cases of remnant gastric cancer using intraoperative indocyanine green fluorescence imaging. The technique allowed visualization of the liver and common bile duct, leading to safe dissection of severe adhesions between hepatobiliary organs and the remnant stomach. This novel approach resulted in successful surgeries without complications, demonstrating the […]

Proximal gastrectomy may be an alternative approach for well-selected patients with proximal gastric cancer following neoadjuvant chemotherapy

Study comparing total and proximal gastrectomy for proximal gastric cancer found that more patients underwent proximal gastrectomy, with a higher likelihood of receiving neoadjuvant chemotherapy. Pathologically, total gastrectomy patients had more advanced tumors and fewer evaluated lymph nodes, but lower margin negativity. Long-term survival did not differ between the two procedures, but neoadjuvant chemotherapy was […]

Impact of Preoperative Anemia on Outcomes in GEP-NET Resections

Patients with preoperative anemia undergoing curative-intent resection for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) had higher rates of major complications and poorer long-term outcomes. Anemia was associated with worse overall survival, while postoperative transfusions were linked to lower overall survival and recurrence-free survival rates. Preoperative anemia affected around one-third of patients and significantly increased the risk of […]

ERAS Protocol Reduces Hospital Stay in Gastric Cancer Surgery

Implementation of enhanced recovery after surgery (ERAS) protocol in distal gastrectomy for gastric cancer significantly reduces adjusted hospital stay without increasing complications. However, no significant differences were observed in long-term nutritional outcomes and quality of life between ERAS and conventional care groups Journal Article by Choi CI, Park JK (…) Kim DH et 4 al. […]

Comparable Long-Term Survival Rates of Endoscopic Therapy and Surgical Resection for 2-5 cm Gastrointestinal Stromal Tumors

In a comparative study of endoscopic therapy (ET) versus surgical resection for 2-5 cm gastrointestinal stromal tumors, long-term outcomes showed no significant difference in overall or cancer-specific survival rates. After propensity score matching, both groups had comparable survival rates, suggesting that ET may be a viable treatment option for these tumors. Further research is needed […]

Potent Nomogram Predicts Lymph Node Involvement in Early Gastric Cancer

A potent nomogram incorporating tumor budding accurately predicts lymph node involvement in early gastric cancer patients, providing exceptional discriminative power and precise predictive capabilities. Tumor budding, along with other clinicopathological factors, demonstrated a robust association with lymph node involvement, improving clinical decision-making by reducing the risk of overtreatment in endoscopic curability C-2. Journal Article by […]