Endoscopic surveillance at 3-year intervals significantly increases the likelihood of detecting early gastric cancer (EGC), with 98% of cases detected within this group. EGC lesions in the short-interval group were smaller, shallower, and had a higher curative resection rate compared to the unchecked group. This demonstrates the importance of regular endoscopic monitoring in improving the […]
Category: Upper Gastrointestinal Tract
Ampicillin-Sulbactam Prophylaxis Benefits Esophagectomy
Antimicrobial prophylaxis with ampicillin-sulbactam was associated with significantly lower rates of surgical site infection, anastomotic leakage, and respiratory failure compared to cefazolin in esophagectomy patients. This choice of antibiotic also led to reduced respiratory complications, shorter hospital stays, and lower total hospitalization costs, with no increase in noninfectious complications. Propensity score matching and instrumental variable […]
Endoscopic Ultrasound-Guided Gastroenterostomy Superior to Enteral Stenting for Malignant Gastric Outlet Obstruction
Endoscopic ultrasound-guided gastroenterostomy was found to be superior to enteral stenting in reducing treatment failure and prolonging time until treatment failure in a propensity score-matched cohort study of patients with malignant gastric outlet obstruction. The study showed a significantly higher treatment failure rate in the enteral stenting group compared to the EUS-GE group, with longer […]
Direct Visual Control of Vacuum Sponges for Esophageal Anastomotic Leaks Treatment
Placing vacuum sponges in esophageal anastomotic leaks using a piggyback technique proved to be a fast and safe alternative to standard methods. In seven patients, 56 eso-sponges® were successfully inserted or replaced with minimal complications, except for one dislocation. All patients healed, except for one unrelated death, and three strictures were effectively treated. This technique […]
En-bloc resection of well-differentiated nonampullary duodenal neuroendocrine tumors is safe and effective
Endoscopic resection of well-differentiated nonampullary duodenal neuroendocrine tumors was safe and effective, with a high rate of en-bloc and R0 resections. Tumors located in the second part of the duodenum, ≥10mm in size, and with muscularis propria invasion were risk factors for non-curative resection. Adverse events were rare and successfully managed. Long-term outcomes showed low […]
Long-Term Survival Unaffected by Complication Severity After Esophagectomy for Cancer
Survival following esophagectomy for esophageal cancer remains stable regardless of post-operative complication severity. A study of 721 patients showed no significant difference in long-term survival rates between those with no complications, minor, or major complications, with overall survival rates staying equivalent at 1, 3, and 5 years. Factors independently associated with survival were gender, comorbidity […]
Impact of Laparoscopic HIPEC on Safety and Perioperative Outcomes in Gastric Cancer with Peritoneal Metastasis
Laparoscopic HIPEC for gastric cancer with peritoneal metastasis is safe and associated with minimal perioperative complications. Approximately one third of patients undergoing initial laparoscopic HIPEC proceeded to cytoreduction and gastrectomy. Preliminary survival data from this study indicate a median overall survival of 11 months from the initial procedure and 19.3 months from the diagnosis, suggesting […]
Why are Intraoperative Adverse Events Important in Robotic Radical Gastrectomy for Gastric Cancer?
Assessment of intraoperative adverse events (IAEs) during robotic radical gastrectomy for gastric cancer revealed that IAEs significantly correlated with postoperative complications and poor long-term prognosis. The presence of IAEs was associated with worse overall and disease-free survival rates compared to patients without IAEs. Utilizing the classintra grading system for quality control and prognostic evaluation is […]
Diagnostic Laparoscopy with Peritoneal Lavage in Gastric Adenocarcinoma: High Diagnostic Yield and Impact on Management
Diagnostic laparoscopy with peritoneal lavage in gastric adenocarcinoma has a high diagnostic yield, with 24.5% of patients having positive findings leading to exclusion from neoadjuvant treatment or surgical resection. Peritoneal metastases were identified in 10.3% of patients, with 12.5% having positive peritoneal cytology without macroscopic disease. Diffuse type carcinoma had the highest risk of peritoneal […]
High waist circumference positively affects clinical outcomes in esophageal cancer patients receiving immune checkpoint inhibitors.
In patients with unresectable or recurrent esophageal cancer receiving immune checkpoint inhibitors, high waist circumference was associated with favorable progression-free survival and disease control rates. This suggests that body composition, specifically waist circumference, may influence clinical outcomes in esophageal cancer patients undergoing ICI treatment. Journal Article by Kosumi K, Baba Y (…) Baba H et […]