An analysis of 4,331 patients undergoing esophagectomy revealed smoking, frailty index, white blood cell count, mckeown esophagectomy, and platelet counts were associated with anastomotic leak. Results showed increased odds of leak with smoking, frailty index scores of 1 or 2, and specific surgical techniques, while higher platelet counts were slightly protective. These findings offer crucial […]

Esophagectomy induces weight loss and improves glucose and lipid metabolism in type 2 diabetes patients. Both diabetic and non-diabetic groups experience similar reductions in weight and BMI post-surgery. Fasting plasma glucose levels decrease significantly in the diabetic group, while HDL levels increase in the non-diabetic group. TG, LDL, and TC levels decrease significantly in both […]

Novel findings suggest that the Tumor Marker Regression Load Score (TMRLS) is a significant independent prognostic factor for gastric cancer patients undergoing neoadjuvant chemotherapy and radical surgery. Patients with high TMRLS who received postoperative adjuvant chemotherapy showed better survival outcomes. The TMRLS-based nomogram demonstrated superior predictive performance compared to traditional staging methods. These results provide […]

The age-adjusted Charlson Comorbidity Index and sarcopenia are significant independent risk factors for prognosis in gastric cancer patients. A new prognostic score, ACCIS, combining these factors, accurately predicts prognosis and enhances predictive accuracy. Integration of ACCI score and sarcopenia improves prognostic predictions, leading to the development of a nomogram with a high concordance index for […]

The preoperative C-reactive protein-albumin-lymphocyte (CAlly) index is an independent prognostic factor for overall and disease-free survival in patients with gastric cancer. It is also a valuable predictive marker for postoperative surgical site infection, highlighting its potential clinical significance in perioperative and oncologic management of gastric cancer patients. Journal Article by Okugawa Y, Ohi M (…) […]

Indocyanine green (ICG) guidance significantly improves lymph node dissection quality in patients with locally advanced gastric cancer undergoing laparoscopic radical gastrectomy after neoadjuvant chemotherapy. ICG led to higher numbers of retrieved lymph nodes, reduced noncompliance rates, and improved lymphadenectomy quality for patients with complete response. Surgical outcomes were similar between ICG and non-ICG groups, suggesting […]

Adding complete mesogastric excision to D2 lymphadenectomy for gastric cancer improves 3-year disease-free survival without significant difference in overall survival rates. Recurrence rates were lower in the complete mesogastric excision group. This finding suggests potential benefits of the combined approach for better outcomes in advanced gastric cancer patients. Comparative Study by Xie D, Shen J […]

In laparoscopic subtotal gastrectomy for gastric cancer, utilizing indocyanine green (ICG) fluorescence for lymph node dissection significantly enhances metastasis detection, with a sensitivity of 75.86% and a high negative predictive value of 97%. The method effectively visualizes lymph nodes, aiding in clinically radical gastrectomy, suggesting its potential as a valuable tool in gastric cancer surgery. […]