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Upper Gastrointestinal Tract

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Upper Gastrointestinal Tract13 Jul 2024

Malnutrition and Nutritional Support After Gastrectomy in Gastric Cancer Patients

Malnutrition, common among gastric cancer patients, can be improved with nutritional support after gastrectomy. Total gastrectomy poses significant challenges, but function-preserving surgeries show promise. Effective nutritional screening and support enhance outcomes, including reduced complications and improved quality of life. Preoperative interventions vary in effectiveness, while…

Ann Surg Oncol12 Jul 2024

Circulating Exosomal MicroRNA Panel Predicts Peritoneal Metastasis in Advanced Gastric Cancer

A circulating exosomal microRNA panel, robustly predicting peritoneal metastasis in advanced gastric cancer patients, was developed and validated with remarkable accuracy. The risk-stratification model, combined with currently used tumor markers, significantly outperformed conventional clinical factors in predicting metastasis. This novel liquid biopsy assay shows potential…

Appendix, Gallbladder and Surgical Emergencies11 Jul 2024

Grading Esophageal Perforations Improves Outcome Predictions

Severely graded esophageal perforations (grades I-IV) impact patient survival differently, with grades II-IV showing lower overall survival rates. Factors such as duration of injury >24 hours, presence of mediastinitis, and esophageal necrosis are associated with unfavorable outcomes. Grading severity based on diagnostic CT scans, endoscopic,…

Eur J Trauma Emerg Surg10 Jul 2024

Omitting Drains Improves Outcomes After Peptic Ulcer Repair

Omitting intraabdominal drains post peptic ulcer repair led to earlier recovery milestones, reduced pain severity, and shorter hospital stay. The no-drain group exhibited faster bowel function return, fluid and solid diet intake, along with decreased morbidity rates such as surgical site infections and respiratory complications…

J Gastrointest Surg9 Jul 2024

Endoscopic Treatments for Gastroesophageal Reflux Disease: EBL and TIF Show Superior Efficacy

Endoscopic band ligation (EBL) and transoral incisionless fundoplication (TIF) show comparable efficacy in improving health-related quality of life in patients with GERD, outperforming other endoscopic interventions like Stretta, EFTP, and Endocinch. EBL and TIF also significantly decrease esophagitis incidence compared to PPIs. While TIF increases…

BMC Surg8 Jul 2024

Robotic-assisted esophagectomy improves R0-resection in esophageal cancer patients

A single-center experience found that robotic-assisted minimally invasive esophagectomy with total mesoesophageal excision led to a significantly higher R0-resection rate compared to open transthoracic esophagectomy. This approach also reduced postoperative pneumonia rates, shortened ICU and hospital stays, with comparable mortality rates. The study suggests that…

Ann Med3 Jul 2024

ERAS Program in Laparoscopic Distal Gastrectomy

ERAS program in laparoscopic distal gastrectomy significantly reduced postoperative recovery time, hospital stays, and costs compared to traditional care. Patients in the ERAS group also had lower postoperative complication rates. Combining ERAS with laparoscopy was safe and effective for managing distal gastric cancer perioperatively. These…

Upper Gastrointestinal Tract3 Jul 2024

Nomogram Model for Predicting Perineural Invasion in Gastric Cancer

Development of a preoperative nomogram model effectively predicts perineural invasion in advanced gastric cancer. Key independent risk factors include extramural vascular invasion, Borrmann classification, tumor thickness, and systemic inflammation response index. The nomogram demonstrates a high AUC value of 0.838, good calibration, and clinical net…

Ann Surg Open2 Jul 2024

Improved Outcomes with Comprehensive Gastric Cancer Surgery Program

Comprehensive regional program, including the mirec pathway, significantly reduced hospital stays after laparoscopic gastrectomy without increasing adverse events. Gastric cancer surgery outcomes improved with decreased hospital stays and lower complication rates. The program revolutionizes care delivery, enhancing quality and value for patients through regionalization, laparoscopic…