Category: Upper Gastrointestinal Tract

Hiatal hernia significantly increases the risk of Barrett’s esophagus, particularly long-segment Barrett’s esophagus

This meta-analysis examined the association between hiatal hernia and Barrett’s esophagus (BE) using 47 studies involving 131,517 participants. The unadjusted data showed that hiatal hernia was significantly associated with an increased risk of any length BE. Furthermore, hiatal hernia was found to be a significant risk factor for BE, particularly long-segment Barrett’s esophagus. These findings […]

Association between Neutrophil to Lymphocyte Ratio and Anastomotic Leak after Gastrointestinal Surgeries

Patients who developed an anastomotic leak (AL) after gastrointestinal surgeries had significantly higher neutrophil to lymphocyte ratio (NLR) levels compared to those who did not. This association was observed in retrospective studies and among white patients, but not consistently in prospective studies and among East Asian patients. These findings suggest a potential link between preoperative […]

Effects of Endovac Therapy on Gastric Conduit Perfusion: Porcine Model Study

The study aimed to assess the effects of endoluminal vacuum sponge therapy (endovac) on gastric conduit perfusion in a porcine model for esophagectomy. The researchers induced ischemia in the gastric conduit and measured tissue perfusion over time. The findings showed that endovac therapy with a pressure of -125 mmHg significantly increased tissue oxygenation and improved […]

Impact of Patient Transfer on Perforated Peptic Ulcer Disease Outcomes: Prolonged Hospital Stay

A study examined the impact of patient transfer for definitive surgical intervention in cases of perforated peptic ulcer disease (PPUD). The analysis found that transferred patients had a significantly longer length of stay compared to non-transfer patients. The average length of hospital stay for transferred patients was over twice as long, with an average of […]

Identification of Clinical Parameters and Evaluation Methods for Anastomotic Leaks in Upper Gastrointestinal Surgery

Researchers conducted a retrospective cohort study on 592 patients who underwent upper gastrointestinal surgeries with an anastomosis. The study aimed to identify clinical parameters that predict anastomotic leaks (AL) and evaluate the effectiveness of investigations in diagnosing AL. The overall occurrence of AL was 6.4%. The presence of a triad including desaturation, tachycardia, and leucocytosis […]

Elective Laparoscopic Paraesophageal Hernia Repair Increases Life Expectancy in Asymptomatic Patients

Elective laparoscopic hernia repair (ELHR) offers a greater increase in life expectancy compared to watchful waiting, particularly in women aged 40 to 90, according to a new markov analysis. The analysis identifies ELHR as the preferred strategy for patients with asymptomatic paraesophageal hernia (PEH) in terms of life-years gained. Sensitivity analysis demonstrates the robustness of […]

High variability in VTE risk across abdominal surgery procedures, impacting thromboprophylaxis decisions

The study conducted systematic reviews and meta-analyses to estimate procedure-specific risks of symptomatic venous thromboembolism (VTE) and major bleeding after various types of abdominal surgery. They found that the risk of VTE varied widely among different procedures, with laparoscopic cholecystectomy having the lowest median risk (

Successful Endoscopic Submucosal Dissection for Barrett’s Neoplasia

Complete circumferential endoscopic submucosal dissection (ESD) was performed on 11 patients with early Barrett’s neoplasia in a Canadian referral center. All procedures were technically successful with en-bloc resection. Nine patients achieved clear margins, while two required esophagectomy due to positive deep margins. The final pathology revealed adenocarcinoma in seven patients, with six cases showing upstaging […]

Telehealth intervention shows potential to improve quality of life for patients with eating symptoms after gastroesophageal cancer surgery

Researchers conducted a pilot study to assess the effectiveness of a telehealth intervention for personalized self-management of eating symptoms after gastroesophageal cancer surgery. The intervention, delivered by a nutritionist through telehealth sessions over 4 months, demonstrated feasibility and acceptability among patients. Although the differences between the intervention and control groups were not statistically significant, the […]

Indocyanine Green Fluorescence in Minimally Invasive Esophagectomy: Predictive Potential and Complication Rates

Indocyanine green fluorescence (IGF) can be used to predict anastomotic complications during minimally invasive esophagectomy (MIE), although its use may be associated with an increased rate of anastomotic leaks and higher mortality. A study of 181 patients undergoing MIE found that patients who underwent IGF evaluation had a higher rate of anastomotic leak compared to […]