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Upper Gastrointestinal Tract

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Esophagus19 Jun 2024

Proton-Based Therapy Equivalent to Surgery for Esophageal Cell Carcinoma

A multi-center study in Japan found that proton-based definitive chemoradiotherapy (p-crt) showed equivalent 3-year overall survival (OS) compared to neoadjuvant chemotherapy followed by esophagectomy (nac-s) in esophageal squamous cell carcinoma patients. While the p-crt group had inferior progression-free survival (PFS), there was better survival in…

Eur J Surg Oncol18 Jun 2024

Nomogram predicts survival in esophageal squamous cell cancer

A nomogram incorporating radiomics and dosiomics features, along with clinical factors, was developed to predict overall survival in esophageal squamous cell carcinoma (ESCC) patients undergoing definitive chemoradiotherapy. Dosiomics features outperformed radiomics features in predicting survival outcomes. The combined model exhibited significant differences in overall survival…

Dig Liver Dis18 Jun 2024

French Intergrup Clinical Practice Guidelines for Ampullary Tumors

French intergroup guidelines provide recommendations for accurate diagnosis, treatment, and follow-up of ampullary tumors based on expert opinions and recent literature review. Emphasizing multidisciplinary approach, guidelines suggest endoscopic papillectomy or surgical papillectomy for adenoma, and pancreaticoduodenectomy for carcinoma. Adjuvant monochemotherapy or polychemotherapy is recommended for…

Appendix, Gallbladder and Surgical Emergencies17 Jun 2024

Fast-track recovery shortens hospital stay after surgery for perforated peptic ulcer

Fast-track recovery post-surgery for perforated peptic ulcer significantly shortened hospital stays without raising postoperative complication risks. A meta-analysis of six trials and 356 patients saw quicker recovery with fewer infections and pulmonary issues in the fast-track group. Overall, fast-track management in this context proved safe…

Surg Endosc16 Jun 2024

Reduced Late Complications After Minimally Invasive Total Gastrectomy

Improved standardized procedures in minimally invasive total gastrectomy led to significantly lower late overall complications in patients with gastric cancer. Late intestinal complications decreased notably, with fewer patients requiring reoperation. The 3-year cumulative incidence rate of late complications was significantly lower post-standardization. This study underscores…

Ann Surg Oncol15 Jun 2024

Benefits of ERAS Protocol in Esophagectomy for Cancer Patients

Comparing outcomes between Enhanced Recovery After Surgery (ERAS) protocol and conventional care in esophagectomy, ERAS patients had fewer complications, shorter hospital stay, and better quality of life scores up to 3 months post-surgery. ERAS group outperformed in functional and symptom domains, showing advantages in dysphagia,…

Upper Gastrointestinal Tract15 Jun 2024

Robot-assisted Surgery Shows Fewer Complications in Gastric Cancer Patients

Meta-analysis comparing robot-assisted and laparoscopic surgery for gastric cancer in patients with high visceral fat area found that robot-assisted procedures had longer operative times but lower major complication rates, including fewer abdominal infections, leaks, and abscesses. No significant differences were observed in hospital stay, blood…

Ann Surg14 Jun 2024

Early Intervention Improves Survival in High Output Chyle Leak After Esophagectomy

Early intervention for high output chyle leak after esophagectomy is crucial for improved survival. A retrospective study revealed that patients who received prompt interventional management had similar overall survival to those without leaks. Late intervention and nonoperative management were linked to increased mortality and longer…

J Gastrointest Surg14 Jun 2024

Nomogram Predicts MSA Explantation Risk

Study developed a nomogram to predict magnetic sphincter augmentation (MSA) explantation, using variables like preoperative demeester score, GERD quality of life score, manometry values, and BMI. The scoring tool helps in preoperative patient selection and treatment decisions, aiding in determining the probability of explantation before…

BMC Surg12 Jun 2024

Enhanced Quality of Life and BMI Maintenance with Double Tract Reconstruction

Double tract reconstruction after proximal gastrectomy demonstrates improved quality of life and better postoperative BMI maintenance, compared to other reconstruction methods. Results show reduced postoperative reflux symptoms, anxiety, and enhanced swallowing ability in the dtr group. Additionally, double tract reconstruction shows satisfactory anti-reflux effects and…