Category: Upper Gastrointestinal Tract

High En-bloc and R0 Resection Rates in Esophageal Cancer

Esophageal cancer patients who underwent endoscopic submucosal dissection (ESD) for T1B tumors showed high en-bloc (100%) and R0 (82.3%) resection rates. Only 23.5% experienced tumor recurrence post-ESD, with safer outcomes in patients receiving additional therapies. Larger studies are necessary to confirm the long-term efficacy of ESD in T1B esophageal cancer. Journal Article by Youssef M, […]

Prognostic Value of Cachexia Index in Oesophagogastric Cancer Patients

A novel prognostic marker, the cachexia index (cxi), is associated with disease progression, postoperative mortality, and overall survival in patients with locally advanced oesophagogastric cancer. Patients with low cxi had higher rates of disease progression, worse postoperative mortality, and decreased overall survival compared to those with normal cxi values. The cxi measurement could aid in […]

13.3% Incidence and Spontaneous Resolution of Gas-Bloat Syndrome Post-Magnetic Sphincter Augmentation

Gas-Bloat Syndrome affects 13.3% of patients at 1 year post-Magnetic Sphincter Augmentation, resulting in worse GERD-HRQL scores, medication use, and satisfaction. However, it resolves spontaneously in the majority of cases, leading to quality-of-life improvement. Patients with preoperative bloating, high GERD-HRQL scores, or smaller device size are at increased risk. Journal Article by Eriksson SE, Ayazi […]

Frailty and TG/PG Increase Risk of Postoperative Pneumonia in Gastric Cancer Patients

Frailty and total or proximal gastrectomy (TG/PG) were found to be independent risk factors for postoperative pneumonia (POP) in patients with gastric cancer undergoing gastrectomy. A simple risk assessment method combining these factors effectively predicted and prepared patients for POP, with a 5.5% incidence rate and an area under the receiver operating characteristic curve of […]

Validation of Textbook Outcome Parameter in Esophageal Cancer Surgery

This study validates textbook outcome (TO) as a quality performance indicator (QPI) for esophageal cancer surgery. Postoperative complications, including Clavien-Dindo grade ≥3 complications, and 30-day readmission rate are associated with reduced survival. Updating TO parameters to include severe complications strengthens its association with increased survival, suggesting the need for a more precise QPI definition in […]

Development of a Nomogram for Preoperative Estimation of Splenic Hilar Lymph Node Metastasis

A high-performing preoperative nomogram for predicting splenic hilar lymph node metastasis in non-greater curvature advanced proximal gastric cancer was developed. Tumor location, size, Borrmann type, and lymphadenectasis were key predictors. The nomogram showed good performance in both training and validation cohorts, aiding surgeons in making informed clinical decisions and leading to improved patient outcomes. Journal […]

Optimizing Treatment and Expanding Indications in Non-Curative Endoscopic Submucosal Dissection

The study highlights the importance of assessing the quality of endoscopic submucosal dissection (ESD) not only for curative cases but also for non-curative ones. With unclear management strategies for Ecurac-1 tumors, research primarily focuses on additional surgical procedures for high-risk patients. Exploring management strategies and follow-up outcomes for non-curative cases and the use of molecular […]

Laparoscopic Gastrectomy in Super-Geriatric Gastric Cancer

Geriatric patients with locally advanced gastric cancer who underwent laparoscopic gastrectomy had lower overall complication rates, shorter hospital stays, and less blood loss compared to those who underwent open gastrectomy. There was no significant difference in 3-year overall survival between the two groups, suggesting laparoscopic gastrectomy may offer similar or better surgical and oncological outcomes […]

Impact of Operative Approach on Recurrence and Survival in Esophageal Cancer

Minimally invasive esophagectomy (TMIE) was associated with improved disease-free survival (DFS) postoperatively compared to open esophagectomy (OE), while both TMIE and hybrid minimally invasive esophagectomy (HMIE) were linked to enhanced overall survival (OS). TMIE showed increased rates of R0 resection and nodal yield, suggesting improved surgical quality. This European multicenter study suggests TMIE as a […]

Reinforcing Hiatal Hernia Repair to Reduce Recurrence Rates

Revision procedures for recurrent hiatal hernia revealed that most recurrences occurred in the left-anterior quadrant of the hiatus. Posterior recurrences were also notable. Both anterior and posterior hiatal reinforcement may be necessary to decrease recurrence rates. A randomized controlled trial using a circular, bio-absorbable mesh is underway to validate this hypothesis. Review by Geerts JH, […]