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Upper Gastrointestinal Tract

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Eur J Surg Oncol12 Mar 2024

Long-Term Survival Unaffected by Complication Severity After Esophagectomy for Cancer

Survival following esophagectomy for esophageal cancer remains stable regardless of post-operative complication severity. A study of 721 patients showed no significant difference in long-term survival rates between those with no complications, minor, or major complications, with overall survival rates staying equivalent at 1, 3, and…

Ann Surg Oncol10 Mar 2024

High waist circumference positively affects clinical outcomes in esophageal cancer patients receiving immune checkpoint inhibitors.

In patients with unresectable or recurrent esophageal cancer receiving immune checkpoint inhibitors, high waist circumference was associated with favorable progression-free survival and disease control rates. This suggests that body composition, specifically waist circumference, may influence clinical outcomes in esophageal cancer patients undergoing ICI treatment.

Surg Endosc9 Mar 2024

Intraoperative Leak Testing Reduces Anastomotic Leakage in Gastric Cancer Surgery

Intraoperative leak testing (IOLT) significantly reduced postoperative anastomotic leakage (PAL) incidence compared to no intraoperative leak testing (NIOLT) in gastric cancer surgery. IOLT was associated with lower rates of anastomotic-related complications and reoperations. These findings suggest that IOLT is a promising tool to improve postoperative…

Eur J Surg Oncol6 Mar 2024

Tumor Volume Fails to Predict Pathologic Response in Esophageal Adenocarcinoma

Researchers analyzed 287 esophageal cancer patients to assess if initial tumor volume on CT scans correlated with histomorphological regression after neoadjuvant therapy. Despite measuring tumor volumes and assessing regression grades, no significant relationship was found. The study concludes that tumor volume does not predict histopathological…