Category: Upper Gastrointestinal Tract

Neoadjuvant Radiation and Pulmonary Complications in Esophagectomy: Impact only in Pre-existing Pulmonary Disease

Patients undergoing esophagectomy for malignancy often experience post-operative pulmonary complications (POPC), and this study aimed to investigate if neoadjuvant radiation therapy contributes to their incidence. The analysis of database files revealed no consistent association between neoadjuvant radiation and POPC in all patients. However, in those with pre-existing pulmonary disease (PEPD), neoadjuvant chemoradiotherapy resulted in a […]

Successful Fistula Closure Achieved through Surgical Management in Complex Duodenal Fistulas

This retrospective study analyzed the management options and outcomes of 50 adult patients with complex duodenal fistulas. Surgical closure combined with duodenal decompression yielded the highest success rate, with 76% of patients achieving fistula closure. In selected cases, nonoperative management was attempted, resulting in closure without surgery in 5 out of 6 patients. However, eventually […]

Higher Lymph Node Count Improves Survival in Stage III Gastric Cancer Patients After Surgery

Analysis of 2373 stage III gastric cancer patients who underwent curative gastrectomy revealed that a higher count of negative lymph nodes (NLN) (>14) significantly improved the 5-year overall survival rate compared to patients with a lower count (43.7% vs 23.1%). This study establishes NLN count as an independent prognostic factor for stage III gastric cancer […]

Lymph Node Tumor Regression Grade (lntrg) is a Better Prognostic Indicator for Esophageal Squamous Cell Carcinoma

Comparing different staging categories for esophageal squamous cell carcinoma, this study determined that lymph node tumor regression grade (lntrg) demonstrated superior prognostic value for disease-free survival prediction compared to pretreatment pathologic n stage (prepn) and posttreatment pathologic n (ypn) categories. lntrg showed significant prognostic stratification power and was an independent prognostic factor. Multivariable cox regression […]

Indocyanine green fluorescence-guided lymphadenectomy improves lymph node retrieval in gastric cancer

The study evaluated the impact of indocyanine green (ICG) fluorescence-guided lymphadenectomy during laparoscopic gastrectomy for gastric cancer. It included 142 patients, with 42 receiving preoperative ICG injection. The ICG group exhibited a higher number of retrieved lymph nodes compared to the non-ICG group, regardless of neoadjuvant treatment or tumor stage. The use of ICG was […]

Primary Surgeon Specialty Does Not Impact Postoperative Complications in Esophagectomy

Cardiothoracic surgeons and general surgeons perform the majority of esophagectomies, but differences in surgical techniques exist. This study analyzed data from 3,247 patients and found that cardiothoracic surgeons were more likely to use traditional minimally invasive or open approaches, while general surgeons favored robotic or hybrid approaches. However, after adjusting for risk factors, there were […]

Low inter-rater reliability and variability in assessing laparoscopic fundoplication with endoscopy

This study evaluated the inter-rater reliability and variability in assessing laparoscopic fundoplication using endoscopy. A total of 101 participants, including upper gastrointestinal surgeons and gastroenterologists, analyzed ten static endoscopic images post-fundoplication. The study found that overall accuracy was 76% for upper gastrointestinal surgeons and 69.9% for gastroenterologists. Upper gastrointestinal surgeons performed significantly better in certain […]

Improved Detection of Lymph Nodes in Esophageal Squamous Cell Carcinoma Using Indocyanine Green-Near-Infrared Fluorescence Imaging

Indocyanine green-near-infrared fluorescence imaging showed a 100% success rate and significantly improved the detection rate of lymph nodes in esophageal squamous cell carcinoma. Seven cases with lymph node metastases were all near-infrared positive, while near-infrared-negative nodes were nonmetastatic. The technique accurately identified sentinel lymph nodes and increased the number of resected mediastinal lymph nodes, suggesting […]

Risk-Scoring Model for Lymph Node Metastasis in T1b-T2 Esophageal Cancer

Researchers constructed and validated a risk-scoring model to predict lymph node metastasis in T1b-T2 esophageal cancer. Multivariate analysis identified primary site, tumor grade, tumor size, depth, and lymphovascular invasion as independent risk factors for lymph node metastasis. The risk-scoring model, based on these factors, showed good predictive accuracy in both the primary cohort and the […]

Learning curve affects long-term quality of life after McKeown minimally invasive esophagectomy

The study investigated the impact of the learning curve on the long-term quality of life (QoL) of esophageal cancer survivors who underwent McKeown minimally invasive esophagectomy (MIE). The results showed that patients in the experienced learning phase had better QoL outcomes, with significant improvements in functional scales and symptom scales related to respiratory and digestive […]