Patients with locally advanced esophageal squamous cell carcinoma (ESCC) who achieved a pathologic complete response (PCR) after neoadjuvant chemotherapy had a favorable prognosis in terms of long-term survival. The 5-year overall survival rate for patients with PCR was significantly higher compared to those without PCR. However, a subset of patients still experienced recurrence, particularly locoregional […]

The study evaluated the influence of tumor size on the prognosis of patients with esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy after neoadjuvant chemotherapy. A total of 272 patients were categorized based on tumor size, with 36mm being the cut-off. Patients with tumor size ≥ 36mm had worse histological response and deeper tumor invasion. In […]

The study analyzed the efficacy of neoadjuvant chemoradiation therapy (ncrt) in patients with completely resectable esophageal squamous cell carcinoma (escc) and minimal lymph node involvement (cN1). The researchers conducted a retrospective review of 247 patients who underwent upfront radical esophagectomy followed by adjuvant treatment. They found that upfront surgery provided accurate nodal staging information, potentially […]

The study compared postoperative complications between neoadjuvant chemotherapy and upfront surgery in gastric adenocarcinoma patients in Finland. Analyzing data from 769 patients, the study found that neoadjuvant chemotherapy did not increase major postoperative complications, including pneumonia, anastomotic complications, wound complications, or other complications. The results suggest that neoadjuvant therapy is not associated with increased postoperative […]

The study developed and validated a procedure-specific competency assessment tool (CAT) for minimally invasive esophagectomy (MIE). The CAT consists of 8 procedural phases, with 4 quality components per phase, assessed using a 1-4 Likert scale. Peer-reviewed MIE videos were evaluated by 18 international experts. Results showed good intrarater reliability and moderate interrater reliability. Construct validity […]

Researchers conducted an international Delphi consensus study to determine expert agreement on the key technical steps of minimally invasive total gastrectomy (MITG) for gastric cancer. A final consensus of 41 statements was reached, outlining crucial steps for performing high-quality MITG for oncological indications. The findings provide a foundation for developing and validating surgical quality assessment […]

Long-term tube feeding intervention after minimally invasive esophagectomy was found to effectively prevent skeletal muscle loss and aid in preventing sarcopenia. The study compared short-term and long-term outcomes of tube feeding intervention in patients who underwent esophagectomy. While there were no significant differences in postoperative albumin levels, body weight, or psoas muscle area between the […]

Comparative study between two tertiary centers in Europe reveals that the time interval from diagnosis to treatment differs significantly between the centers. The main reasons for these differences are the need for additional diagnostics and variations in referral routines. Gastroscopy was frequently repeated for further anatomical mapping. Clearer protocols, checklists, and guidelines can contribute to […]