The study evaluated the outcomes and predictors of treatment failure in patients undergoing anti-reflux mucosectomy for gastroesophageal reflux disease. The results showed that the procedure significantly improved quality of life, with symptom improvement and resolution in a majority of patients. However, symptom resolution did not always correlate with objective reflux control. Current smoking status was […]
Category: Upper Gastrointestinal Tract
Correlation between main and minor lesions of synchronous multiple gastric neoplasms
Researchers analyzed data from patients with early gastric cancer (EGC) who underwent endoscopic submucosal dissection (ESD) to assess the correlation between main and minor lesions of synchronous multiple gastric neoplasms (SMGNs). Among the 1013 post-ESD cases examined, 95 cases had SMGN. The study revealed a similarity in pathological type (rs = 0.37) and a positive correlation in […]
Percutaneous Creation of Gastrointestinal Anastomosis via Lumen-Apposing Metallic Stents for Gallbladder Drainage
Researchers discuss the emerging frontier of percutaneous cholecysto-enteric anastomoses for internal drainage of the gallbladder, focusing on the percutaneous delivery and deployment of lumen-apposing metallic stents. The study highlights the efficacy and safety of using these stents for creating gastrointestinal anastomosis, providing a less invasive option for gallbladder drainage compared to traditional surgical procedures. Journal […]
Supraclavicular Lymph Node Metastases in Esophageal Squamous Cell Carcinoma: Limited Impact on OS After Three-Field Dissection
The study aimed to determine the impact of clinically suspicious and pathologically confirmed supraclavicular lymph node (SCN) metastasis on survival outcomes in esophageal squamous cell carcinoma (ESCC) patients who underwent esophagectomy with three-field lymph node dissection. Analysis of 611 patients revealed that the presence of SCN metastasis did not significantly affect overall survival, regardless of […]
Classification of GIST and Other Benign Gastric Tumors for Minimally Invasive Surgery
The study aimed to propose a new surgical classification for non-malignant gastrointestinal mesenchymal tumors (GMTs) based on their location and guide minimally invasive surgical strategies. The classification divided the tumors into two groups (exophytic and transmural/intragastric) and further subdivided them based on location. The study included 42 patients distributed into each subgroup. Encouraging perioperative outcomes […]
Survival Advantage of Multivisceral Resection in Locally Advanced Gastric Cancer
Patients with locally advanced gastric cancer often require multivisceral resection to achieve complete tumor removal. A systematic review of 30 studies including 3362 patients showed that R0 resection was achieved in 67.77% of cases, with the spleen, colon, and pancreas being the most frequently resected organs. The most common postoperative complications were pancreatic fistulae, intraabdominal […]
High Incidence of Pancreatic Exocrine Insufficiency After Non-Pancreatic Upper Gastrointestinal Surgery: Implications for Enzyme Replacement Therapy
Approximately 36% of patients who undergo non-pancreatic upper gastrointestinal surgeries develop pancreatic exocrine insufficiency (PEI), which can have detrimental effects on their health. The incidence of PEI was found to be 23% after bariatric metabolic surgery and 50.4% after oesophagogastric resection, with even higher rates after certain procedures. Diagnostic testing using fecal elastase 1 was […]
Management and Prognosis of Gastric Neuroendocrine Tumors
Gastric neuroendocrine tumors (G-NETs) are rare tumors originating from the gastric mucosa, classified into three subtypes based on their characteristics and behavior. Type 1 and 2 are typically multifocal and associated with elevated serum gastrin levels. Type 2 causes symptoms like abdominal pain and diarrhea. Type 3, sporadic and solitary, has the most aggressive phenotype. […]
High-resolution 3D CT Aids in Hiatal Hernia Diagnosis and Surgical Planning
The study demonstrates that high-resolution 3D computed tomography (CT) is a valuable tool for assessing the anatomical characteristics of hiatal hernias (HH) and aiding in surgical planning for laparoscopic or robotic antireflux procedures. CT scans accurately identified HH in 70% of patients and correlated well with endoscopic findings. Furthermore, the distance between the esophagogastric junction […]
Optimal extent of lymphadenectomy in esophageal cancer surgery: Controversy and evidence
The current curative multimodal treatment of advanced esophageal cancers includes neoadjuvant or perioperative chemo(radio)therapy and radical surgical resection with a 2- or 3-field lymphadenectomy. Lymph node involvement is a significant predictor of long-term survival in esophageal cancer patients. The distribution pattern of lymph node metastases is unpredictable and depends on various factors. The extent of […]