Category: Wounds

Combining PRP and NPWT enhances healing in pressure ulcers

A combination of autologous platelet-rich plasma (PRP) and negative pressure wound therapy (NPWT) demonstrates superior efficacy in treating pressure ulcers. In a study involving 90 patients, the combined treatment resulted in a 95.56% effective rate, significantly higher than the 80.00% found with NPWT alone. The combination also led to reduced infection control times, shorter wound […]

Telemedicine enhances outpatient chronic wound management

A novel outpatient wound management model integrating telemedicine and ambulatory care is being examined to enhance service quality for older and vulnerable populations. The study employs a whole-system approach that includes economic evaluations and qualitative insights from healthcare providers and patients. Initial findings from baseline interviews and fieldwork indicate potential improvements in care delivery compared […]

Early surgical intervention is critical in necrotizing fasciitis outcomes

In a cohort of 171 patients with necrotizing fasciitis, a high mortality rate was observed, particularly in individuals with elevated LRINEC scores and procalcitonin levels. Key findings revealed that early extensive surgical debridement is essential for improving patient survival, independent of disease severity. Streptococcus pyogenes was frequently identified, and 69% of patients presented with a […]

Prophylactic negative pressure wound therapy may reduce infections.

A multicenter randomized trial aims to determine if prophylactic negative pressure wound therapy (NPWT) decreases postoperative wound complications in midline laparotomy patients. The trial will compare standard dressings with NPWT devices, involving 2013 patients over 36 months. By addressing the prevalence of surgical site infections and their associated healthcare costs, the study seeks to provide […]

Vacuum-assisted wound closure with mesh shows better outcomes

Findings indicate that vacuum-assisted wound closure with mesh-mediated fascial traction (vawcm) significantly improves primary fascial closure success rates (70% vs. 36%) and reduces in-hospital mortality (26% vs. 72%) compared to traditional vacuum-assisted wound closure (vawc) only. Multivariate analysis confirms vawcm’s role as an independent factor linked to lower mortality (odds ratio, 0.14; p = 0.004). These results […]

Subcutaneous Drain Reduces Surgical Site Infections in Abdominal Wound Closure

Patients with secondary peritonitis who received a subcutaneous drain post-laparotomy had a significantly lower incidence of incisional surgical site infections (20% vs. 68%) and shorter hospital stays (8.96 days vs. 14.04 days) compared to those without the drain. Although not statistically significant, the drain also reduced the risk of wound dehiscence. Subcutaneous suction drainage is […]

Abdominal wound length impacts postoperative recovery in colorectal cancer patients

Abdominal wound length significantly affects the time of first flatus passage, hospital stay length, and cytokine levels among colorectal cancer patients. Smaller wounds and lower postoperative interleukin-6 levels are associated with quicker recovery and shorter hospital stays. This study highlights the intricate relationship between wound length, cytokine levels, and patient outcomes, emphasizing the importance of […]

Heart-shaped Tension-Reducing Suture Shows Promising Outcomes in Hypertrophic Scar Repair

Heart-shaped tension-reducing suture combined with lbd suturing technique led to improved scar quality in hypertrophic scar patients. Results showed reduction in scar width, significant enhancements in scar assessment scores, and higher levels of patient satisfaction postoperatively. This novel approach demonstrated better outcomes in color, stiffness, thickness, and overall scar opinion, highlighting its clinical efficacy and […]

Chlorhexidine Gluconate Reduces Incisional Infections

Subcutaneous wound soaking with chlorhexidine gluconate significantly reduces the incidence of incisional surgical site infections in patients undergoing gastroenterological surgery. A randomized controlled trial involving 363 patients showed a lower infection rate with chlorhexidine gluconate compared to the control group. This study highlights the effectiveness of chlorhexidine gluconate in preventing surgical site infections in gastroenterological […]

Prognostic Value of Lymphocyte-to-C-Reactive Protein Ratio in Fournier’s Gangrene

Younger patients with low lymphocyte-to-C-reactive protein ratio had better survival rates in Fournier’s gangrene. Higher hospital costs correlate with increased mortality risk. The Fournier’s Gangrene Severity Index, lymphocyte-to-C-reactive protein ratio, and neutrophil-lymphocyte ratio were effective at predicting patient outcomes. A low lymphocyte-to-C-reactive protein ratio was identified as a potential marker for assessing mortality and disease […]