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Outcomes of Right and Left 6-Segmentectomies for Liver Tumors

Right (H145678) and Left (H123458) 6-segmentectomies show potential for long-term survival in select patients with malignant liver tumors.

  • Surgical futility occurred in 15.6%, with failure-to-rescue rates at 30.3%.
  • Achieved textbook outcomes in 30.8% of patients, with a median follow-up of 26 months.
  • 5-year overall survival at 30.8% and disease-free survival at 18.9%.

Consider targeted strategies to enhance outcomes and patient selection, as liver transplantation is not viable for most cases.

Journal Article by Azoulay D, Corleone P (…) Salloum C et 15 al. in Ann Surg

Copyright © 2026 Wolters Kluwer Health, LLC. All rights reserved.

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Novel Radiation Approach Elevates Outcomes in Locally Advanced Pancreatic Cancer

Hypofractionated ablative radiation therapy before surgery improves overall survival in locally advanced pancreatic cancer.

  • 38% overall survival at 2 years; 54% for those who underwent resection.
  • Only 11% local progression and 73% distant metastasis rates at 2 years.

This strategy shows no increase in surgical morbidity, making it significant for patient selection and preoperative planning in LAPC.

  • 94% of participants received mFOLFIRINOX, highlighting effective induction therapy prior to radiation.

Journal Article by Reyngold M, Wei AC (…) Crane CH et 20 al. in JAMA Surg

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Survival Advantage with Neoadjuvant Chemotherapy in Esophageal Cancer

Neoadjuvant chemotherapy (NCT) significantly improves long-term survival in patients with esophageal and esophagogastric junction adenocarcinoma compared to chemoradiotherapy (NCRT).

  • Overall survival rates at 1, 3, and 5 years with NCT were 95.4%, 81.5%, and 73.8% versus 87.8%, 64.8%, and 56% for NCRT (p < 0.001).
  • Disease-free survival also favored NCT, with a substantially reduced risk of death (HR 0.49, p < 0.001) and recurrence (HR 0.24, p < 0.001).

Consider the type of neoadjuvant therapy when discussing prognosis with patients.

Journal Article by Risi L, De Martino R (…) Garbarino GM et 6 al. in Ann Surg Oncol

© 2026. The Author(s).

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Acute Colonic Ischemia Risks After Colectomy for Cancer

Postoperative colonic ischemia is rare but significantly impacts outcomes after elective colectomy for colorectal cancer.

  • Occurred in 0.27% of patients; highest rates seen in left hemicolectomy (0.52%) and transverse colectomy (0.47%).
  • Patients with ischemia had a median Charlson comorbidity index of 3 versus 2 in those without (p < .001).
  • It is linked to a 20.2% reoperation rate and 23.5% in-hospital mortality, compared to 0.96% and 0.95%, respectively, in non-ischemic cases.

Surgeons should consider vascular comorbidities and resection types when assessing patient risk and consider intraoperative perfusion techniques to minimize complications.

Journal Article by Rivera-Valerio M, Zeineddin A (…) Nembhard C et 2 al. in BMC Surg

Copyright © 2026 Elsevier Inc. All rights reserved.

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Hem-o-lok Clips Outperform Endoloops for Appendiceal Closure

Hem-o-lok clips provide a safer and faster option for appendiceal stump closure in laparoscopic appendectomy compared to endoloops.

  • Intra-abdominal abscess formation was 1.87 times less likely with hem-o-lok clips (p=0.035).
  • Operative time was significantly shorter by an average of 5.41 minutes (p=0.019).

Surgeons may consider hem-o-lok clips for improved outcomes and efficiency in appendectomies.

  • No significant differences were found in surgical site infections or hospital stays between techniques.

Review by Karacan E and Yılmaz EM in Surg Endosc

© 2026. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Biomarkers for Recurrent Rectal Cancer Outcomes

Identifying molecular biomarkers could enhance patient selection for salvage surgery in locally recurrent rectal cancer, impacting surgical strategies and patient outcomes.

  • Locoregional recurrence rates after surgery ranged from 15% to 52% over 3-5 years.
  • Five-year overall survival rates varied from 22% to 53%.

Surgeons should consider serum biomarkers like CEA and CA19-9, linked to poor survival, for patient risk assessment.

  • Elevated CEA was associated with shorter overall survival in 11 studies.
  • Contemporary biomarkers remain unstudied in this population, indicating a research gap.

Review by Vu JK, Younan E (…) Brown KGM et 7 al. in Ann Surg Oncol

© 2026. The Author(s).

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Rethinking Surgical Oncology Fellowship Training

Surgical oncology fellowships need to evolve to meet the actual career paths of graduates.

  • Current selection favors research, but most trainees intend to focus on clinical practice.
  • Only a small percentage of fellows achieve long-term research productivity despite extensive dedicated research time.

Adapting fellowships to include clinically intensive tracks could better prepare surgeons for today’s workforce demands.

  • Proposed changes include reevaluating selection criteria to prioritize clinical skills and holistic evaluations.

Editorial by Yopp AC, JZeh H (…) Berman RS et 5 al. in Ann Surg Oncol

© 2026. Society of Surgical Oncology.

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Redo Hepatic Vein Reconstruction Effective for Liver Metastases

Late-onset venous stenosis after hepatic vein reconstruction may signal tumor recurrence, impacting how you monitor and treat patients.

  • In a study of 72 reconstructed veins, 19 developed stenosis: 14 due to technical issues, and 5 linked to tumor recurrence.
  • Technical stenoses occurred within 6 months, whereas late stenoses were associated with tumor recurrence detected years later.

Surgeons should maintain a high index of suspicion for recurrent disease in patients with late venous stenosis.

  • Redo reconstruction is viable, as demonstrated in a case involving a 49-year-old woman with unresectable rectal cancer.

Journal Article by Sawa Y, Ono Y (…) Takahashi Y et 10 al. in Ann Surg Oncol

© 2026. Society of Surgical Oncology.

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New technique safely guides liver surgery in rare anatomy

Surgeons can effectively navigate complex liver anatomy using the Arantius-first approach, particularly with right-sided ligamentum teres (RSLT).

  • RSLT occurs in about 0.43% of patients, complicating conventional techniques.
  • The Arantius-first approach enhances visibility and control, reducing the risk of injuries during laparoscopic left hemi-hepatectomy.

Effective application of this method can improve surgical outcomes in patients with atypical anatomical variations.

  • A successful case involved an 80-year-old man with hepatocellular carcinoma, demonstrating the technique’s practicality.

Journal Article by Kubo H, Ashida R (…) Sugiura T et 6 al. in Surg Endosc

© 2026. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Training Gaps in Robotic Surgery Across Specialties

Robotic training varies significantly among general surgery, gynecology, and urology residents, affecting their confidence and preparedness.

  • Current general surgery residents report 89.5% satisfaction and 27.8% confidence in training, compared to 37.5% satisfaction and 75% confidence in gynecology.
  • Urology residents have 76.7 bedside cases and 195.4 console cases per resident, vastly outpacing general surgery (2.2 bedside, 30.2 console) and gynecology (3.1 bedside, 41.7 console).

Focus on enhancing robotic case exposure in residency programs is essential to meet surgical demands.

Journal Article by Makope A, Francis J, Schaefer M and Higgins RM in Surg Endosc

© 2026. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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