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Side-to-side anastomosis reduces postoperative bleeding better than end-to-side

A systematic review involving 14,555 participants reveals that side-to-side anastomosis (SSA) is more effective than end-to-side anastomosis (ESA) in reducing postoperative anastomotic bleeding during laparoscopic right hemicolectomy for cancer patients. No significant differences were found in overall anastomotic complications, though SSA was advantageous in minimizing bleeding. Conversely, ESA showed potential benefits for reducing anastomotic leakage and intestinal obstruction, albeit without statistical significance. Overall, specific advantages exist for both techniques.

Comparative Study by Zhang XQ, Tang RX (…) Ji GY et 4 al. in Int J Colorectal Dis

© 2025. The Author(s).

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Liver resection outperforms radiofrequency ablation for small tumors

A systematic review and meta-analysis comparing liver resection (LR) and radiofrequency ablation (RFA) for solitary hepatocellular carcinoma (HCC) ≤3 cm highlights that LR offers superior overall survival, disease-free survival, and recurrence-free survival compared to RFA, particularly for lesions ≤2 cm. While no significant differences were found in randomized controlled trials, cohort studies indicated LR’s advantages, establishing it as the preferable option for small HCC treatment. Additional randomized trials are necessary to confirm these findings.

Journal Article by Yang M, Li G (…) Wang W et 3 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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External-beam radiation therapy improves outcomes in liver cancer patients

Recent findings reveal that external-beam radiation therapy (EBRT) significantly enhances patient outcomes in hepatocellular carcinoma, addressing critical care gaps. Randomized trials show that EBRT boosts overall survival and recurrence-free survival compared to conventional treatments, particularly when combined with sorafenib. Additionally, it improves the quality of life for patients with painful tumors. As technology advances, guidelines need to integrate EBRT’s expanding role in treatment for both early and advanced liver cancer stages.

Review by Dudzinski SO, Newman NB (…) Ludmir EB et 10 al. in Lancet Gastroenterol Hepatol

Copyright © 2025 Elsevier Ltd. All rights reserved, including those for text and data mining, AI training, and similar technologies.

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Cytoreductive surgery with HIPEC and IORT enhances gastric cancer survival

Findings indicate that cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) and intraoperative radiation therapy (IORT) significantly improves overall survival (63 months) and disease-free survival (87 months) for gastric cancer patients. Over one-third of participants experienced no postoperative complications, while those who did faced a median of just one complication, primarily grade II. The absence of in-hospital mortality underscores the treatment’s safety profile alongside its efficacy.

Journal Article by Alaswad MM, Arabi TZ (…) Amin TM et 11 al. in World J Surg Oncol

© 2025. The Author(s).

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Colorectal cancer screening efforts aim to reduce disparities.

Colorectal cancer mortality in underserved regions of Washington shows alarming trends, with non-white patients dying 8 years earlier than their counterparts. A significant 40% drop in screenings was noted post-pandemic. Targeted outreach initiatives, including presence at local health fairs and farmers’ markets, aim to engage rural Hispanic communities. By collaborating with local leaders and offering hands-on training, the project aspires to enhance education and raise screening rates, addressing persistent health disparities.

Review by Duffy L, Anderson M (…) Kumar A et 5 al. in Am J Surg

Copyright © 2025 Elsevier Inc. All rights reserved.

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Machine learning model effectively predicts postoperative recurrence in duodenal adenocarcinoma

A machine learning-based model has been developed to predict postoperative recurrence in patients with duodenal adenocarcinoma, utilizing data from 1,830 patients who underwent radical surgery. Among 100 predictive models tested, the penalized regression + accelerated oblique random survival forest model (pam) delivered the highest performance with a concordance index (c-index) of 0.882 in the training cohort. This tool aims to assist clinicians in evaluating disease severity and planning follow-up and adjuvant treatments.

Journal Article by Liu X, Xiao Q (…) Zhang J et 16 al. in BMC Med

© 2025. The Author(s).

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Key factors predict failure to achieve textbook outcomes post-surgery

A systematic review and meta-analysis revealed five significant risk factors linked to failure in achieving textbook outcomes following pancreatoduodenectomy. Key contributors include preoperative biliary drainage, smaller tumor size, soft pancreatic texture, small pancreatic duct diameter, and increased intraoperative blood loss. These findings, synthesized from ten studies involving over 5,000 patients, aim to assist surgeons in identifying high-risk patients and enhancing surgical strategies and perioperative management to improve overall outcomes.

Journal Article by Yuan J, Du C (…) Li J et 5 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Laparoscopic two-stage algorithm proves safe for gallbladder cancer

The novel two-stage laparoscopic algorithm evaluated in 40 patients with suspected gallbladder cancer demonstrated safety and feasibility. Procedures included laparoscopic whole-layer cholecystectomy for early-stage lesions and gallbladder bed resection for uncertain borders. Median operation time was 165 minutes with minimal blood loss, and no bile leakage occurred. Histological evaluation confirmed gallbladder cancer in 16 patients, with several undergoing additional lymphadenectomy. This approach highlights an effective strategy for optimizing treatment outcomes in gallbladder cancer cases.

Journal Article by Tokumitsu Y, Kawaoka T (…) Nagano H et 13 al. in Updates Surg

© 2025. Italian Society of Surgery (SIC).

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Damage control techniques prove effective for unexpected massive bleeding

The study illustrates the efficacy of damage control techniques (DCS) in managing unexpected massive bleeding during elective surgeries. Two cases are presented: an obese male with colon cancer and a male with hepatocellular carcinoma, both experiencing significant bleeding. DCS facilitated stabilization in life-threatening scenarios, enabling successful interventions despite hemodynamic instability and coagulopathy. Outcomes were favorable, as both patients survived post-surgery, underscoring the importance of DCS in elective surgeries facing unforeseen complications.

Journal Article by Nanashima A, Wada T (…) Furukawa K et 3 al. in Int J Surg Case Rep

Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.

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Electroacupuncture significantly reduces postoperative ileus duration.

In a multicenter trial involving 585 patients undergoing laparoscopic gastrectomy for gastric cancer, electroacupuncture (EA) proved effective in reducing postoperative ileus (POI) duration. EA decreased the time to first flatus by over 12 hours compared to sham treatments and standard care, and it shortened the time to first defecation by approximately 15 hours. Additionally, the incidence of prolonged POI was lower in the EA group. No severe adverse events occurred, confirming EA’s safety.

Journal Article by Pei L, Wang G (…) Sun J et 13 al. in Gastroenterology

Copyright © 2025 AGA Institute. Published by Elsevier Inc. All rights reserved.

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