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Primary repair leads to lower severe sepsis rates post-colon injury

Patients with complete spinal cord injury and colon injuries demonstrate reduced severe sepsis risk when undergoing primary repair or resection with primary anastomosis, compared to those receiving colostomy. In a study involving 99 colostomy patients matched with 215 undergoing primary repair, severe sepsis occurred in 13.1% versus 4.2%, respectively. This highlights the significance of surgical choice in minimizing postoperative complications for individuals with combined spinal cord and colon injuries.

Journal Article by Huang W, Braschi C (…) Demetriades D et 2 al. in Am J Surg

Copyright © 2025 Elsevier Inc. All rights reserved.

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ALBI-GGT Score Improves Prognostic Accuracy for HCC Patients

A novel ALBI-GGT score was developed to enhance prognostic accuracy for patients undergoing hepatocellular carcinoma (HCC) resection. This composite score combines the albumin-bilirubin and gamma-glutamyl transferase metrics, showing superior predictive ability for long-term survival compared to either measure alone. In multivariable analysis, both components significantly predicted overall mortality, with the ALBI-GGT score achieving the highest predictive accuracy (c-index: 0.68) and effectively stratifying patients into distinct survival groups.

Journal Article by Akabane M, Kawashima J (…) Pawlik TM et 19 al. in J Gastrointest Surg

Copyright © 2025. Published by Elsevier Inc.

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Antiviral therapy significantly lowers late recurrence in HBV-related HCC

A retrospective cohort study revealed that antiviral therapy (AVT) markedly reduces late recurrence rates in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) and compensated cirrhosis post-hepatectomy. The 1-, 3-, 5-, and 10-year recurrence rates for the AVT group were significantly lower than those of the non-AVT group (26%, 49%, 65%, and 76% vs. 29%, 69%, 87%, and 92%, p < 0.001). Patients exhibiting a persistent virological response experienced the most favorable outcomes.

Journal Article by Liu J, Bai S (…) Li J et 11 al. in Eur J Surg Oncol

Copyright © 2025. Published by Elsevier Ltd.

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Minimal bleeding risks observed with Factor Xa inhibitor management

A multicenter cohort study involving 1,902 patients with atrial fibrillation found that discontinuing Factor Xa inhibitors before low-risk procedures results in minimal complications. Following the Perioperative Factor Xa Inhibitor Discontinuation protocol, rates of major bleeding were just 0.1%, and no thromboembolic events occurred within 30 days post-procedure. These findings support a standardized approach for managing oral anticoagulant therapy in patients undergoing procedures where bleeding risk is low.

Multicenter Study by Lee SR, Lee KY (…) Choi EK et 12 al. in JAMA Netw Open

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Ergonomic training improves surgeons’ well-being and career longevity

Significant improvements in pain, physical workload, depression, and quality of life were observed in surgeons after completing ergonomic training and posture exercises. Following a one-month intervention, participants demonstrated enhanced awareness of ergonomic practices, leading to reduced musculoskeletal disorders. The study highlights the critical need for surgical professionals to adopt proper posture and endurance training to mitigate fatigue and discomfort linked to ergonomic challenges in the operating room.

Journal Article by Külekçioğlu S and Dilektaşlı E in Turk J Surg

Copyright © 2024, Turkish Surgical Society.

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Telemedicine significantly reduces outpatient waiting times.

A systematic review revealed telemedicine’s effectiveness in decreasing outpatient wait times, showcasing a substantial weighted mean reduction of 25.4 days across 270,388 patients. Notably, for clinical specialties, the reduction reached 34.7 days, and for surgical patients, it was 17.3 days. Most studies demonstrated low bias risk, underscoring telemedicine’s potential for enhancing equitable access to healthcare and improving efficiency in service delivery.

Systematic Review by Capodici A, Noci F (…) Giannoni A et 5 al. in BMJ Open

© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.

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Key risk factors identified for predicting complications after pancreatoduodenectomy

A comprehensive review found that the main pancreatic duct diameter and pancreatic texture are critical for predicting postoperative pancreatic fistula, while age and ASA score are significant for other complications. Of 90 studies evaluated, only 26% of risk stratification tools had external validation, with even fewer (20%) for artificial intelligence models. The findings emphasize the need for enhanced validation of these risk models to facilitate effective clinical implementation and informed surgical decision-making.

Review by Alhulaili ZM, Pleijhuis RG (…) Klaase JM et 2 al. in Langenbecks Arch Surg

© 2025. The Author(s).

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Prediction models for disease-free survival in colon cancer

A prospective study developed and validated pre- and post-operative models for predicting disease-free survival (DFS) after curative right-sided hemicolectomy in colorectal cancer patients. The study tracked 822 patients, revealing 1, 3, and 5-year DFS rates of 85.6%, 72.5%, and 57.6%, respectively. Key risk factors for recurrence included increasing age, male gender, and advanced disease stage. The models, with c-index values of 0.75 and 0.78, aim to enhance risk stratification and treatment decisions.

Journal Article by Lucocq J, Trinder T (…) Muthukumarasamy G et 3 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Preoperative NLR and PLR predict colorectal cancer prognosis

Analysis of 1,016 colorectal cancer patients revealed that preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) serve as significant predictors for long-term outcomes, particularly in anastomotic leakage cases. A cutoff of NLR ≥2.89 and PLR ≥157.62 indicated poor survival prognosis. Kaplan-Meier survival curves demonstrated significantly higher 5-year overall and disease-free survival rates in patients with lower NLR and PLR. Calibration and decision curves further validated the predictive accuracy of these models for overall survival and disease-free survival.

Journal Article by Xu N, Zhang JX (…) Jin WD et 4 al. in BMC Surg

© 2025. The Author(s).

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ASAP Score Predicts Recurrence in Hepatocellular Carcinoma Patients

The ASAP score, evaluated in a cohort of 1,239 patients undergoing hepatic resection for hepatocellular carcinoma (HCC), revealed significant prognostic value. A cutoff of 4.8 classified patients into high and low-risk groups, showing that those with higher scores faced significantly greater 5-year recurrence rates (73.9% vs. 51.0%). The study establishes the ASAP score’s role in predicting postoperative outcomes, emphasizing its potential to enhance management and surveillance strategies for HCC patients.

Journal Article by Yang T, Yin DX (…) Shen F et 16 al. in J Clin Exp Hepatol

© 2024 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

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