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Real-time organ hypoperfusion detection with Indocyanine Green

Real-time organ hypoperfusion detection using Indocyanine Green in a piglet model showed immediate decreases in oscillation signals in most organs when peripheral arterial supply was occluded. Complete disappearance of oscillation curves was observed when central arterial supply was blocked. Continuous monitoring using high-frequency, low-dose ICG bolus regimen successfully detected organ hypoperfusion in real-time, offering potential for improved surgical decision-making.

Journal Article by Oppermann C, Dohrn N (…) Gögenur I et 3 al. in Surg Endosc

© 2024. The Author(s).

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Digitizing Surgical Data Delivery in Tanzanian Hospitals

Digitizing operating theater data at Tanzanian referral hospital showcased significant advancements in data management, with over 4449 procedures conducted, emphasizing orthopedics/trauma. Challenges included securing local support and technology integration, but lessons learned highlighted the importance of stakeholder communication and training. The success of the web-based platform suggests scalability potential, with recommendations for ongoing monitoring, local funding, and global partnerships to ensure sustainability.

Journal Article by Osebo C, Razek T (…) Boniface R et 4 al. in World J Surg

© 2024 The Author(s). World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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Feasibility of Laparoscopic Common Bile Duct Exploration in Gastric Bypass Patients

Study shows laparoscopic exploration with a disposable bronchoscope is safe and effective for removing common bile duct stones in gastric bypass patients, achieving 100% stone clearance without conversions to open surgery. This cost-effective approach offers a practical alternative to traditional methods, demonstrating feasibility and safety in this population.

Journal Article by Jazi AHD, Mahjoubi M (…) Adib R et 3 al. in Obes Surg

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Positive outcomes of two-stage hepatectomy for colorectal liver metastasis in Japanese patients

Two-stage hepatectomy with portal vein embolization in Japanese patients with colorectal liver metastasis showed a 1-, 3-, and 5-year overall survival rate of 92.5%, 70.8%, and 34.7%. Patients with more than 10 liver nodules had a 4.2-fold increased mortality risk. Repeat hepatectomy post-tsh was more beneficial than chemotherapy. The study confirms tsh as a safe procedure with acceptable outcomes and suggests repeat hepatectomy as a salvage treatment for relapse.

Journal Article by Shimizu T, Aoki T (…) Ajioka Y et 22 al. in Int J Surg

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.

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Improved Efficacy in Treating Large Hepatocellular Carcinoma with Major Portal Vein Tumor Thrombosis

A study comparing lenvatinib plus drug-eluting bead transarterial chemoembolization with and without hepatic arterial infusion chemotherapy for hepatocellular carcinoma > 7.0 cm with major portal vein tumor thrombosis found that the addition of haic significantly improved objective response rate, time to progression, and overall survival, with a comparable safety profile.

Journal Article by Cai M, Liang L (…) Zhu K et 13 al. in Int J Surg

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.

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Robotic Liver Surgery Outcomes in Elderly Patients

Robotic liver surgery in elderly patients leads to less blood loss and shorter hospital stays compared to open liver surgery, especially in minor liver resections. Overall morbidity is similar between the two groups, but operative times are longer with the robotic approach. These findings highlight the safety and feasibility of robotic liver surgery for elderly patients with liver tumors, offering potential benefits in terms of postoperative recovery.

Journal Article by Fukumori D, Tschuor C (…) Nørgaard Larsen P et 4 al. in J Hepatobiliary Pancreat Sci

© 2024 The Author(s). Journal of Hepato‐Biliary‐Pancreatic Sciences published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Hepato‐Biliary‐Pancreatic Surgery.

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Neutrophil to Lymphocyte Ratio Predicts Bowel Ischemia in Non-Strangulated Adhesive Small Bowel Occlusions

Neutrophil to lymphocyte ratio (NLR) > 6.8 was identified as the sole independent predictive factor for bowel ischemia in non-strangulated adhesive small bowel obstruction, with 78% sensitivity and 65% specificity. This study highlights the importance of NLR as a straightforward and reproducible parameter in predicting bowel ischemia onset, aiding acute care surgeons in early detection and management in cases of conservative treatment failure.

Journal Article by Friziero A, Rosso E (…) Sperti C et 9 al. in BMC Surg

© 2024. The Author(s).

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Reduction of Surgical Complications with Piperacillin/Tazobactam in Pancreatoduodenectomy

A meta-analysis comparing piperacillin/tazobactam and traditional antibiotics for surgical prophylaxis during pancreatoduodenectomy showed significant reductions in surgical-site infections, major complications, postoperative pancreatic fistulas, and mortality in patients receiving piperacillin/tazobactam. Subgroup analysis demonstrated reduced incidences of superficial and organ/space infections. These findings support the use of piperacillin/tazobactam to decrease postoperative complications and enhance patient outcomes following pancreatoduodenectomy.

Systematic Review by Kumar J, Reccia I (…) Llaguna O et 10 al. in BJS Open

© The Author(s) 2024. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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Long-Term Outcomes of Additional Surgery for T1 Colorectal Cancer

Study comparing long-term outcomes of patients treated with additional surgery after endoscopic resection versus primary surgery for T1 colorectal cancer found no adverse effects on overall survival rates. The 5-year survival rates were 97.1% in the additional surgery group and 96.0% in the primary surgery group, indicating non-inferiority. Additionally, recurrence rates showed no significant difference between the two groups. Endoscopic resection remains a viable treatment option for T1 colorectal cancer patients.

Journal Article by Tamaru Y, Kuwai T (…) Ueno H et 38 al. in Am J Gastroenterol

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.

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Delayed Adjuvant Chemotherapy Linked to Poorer Colorectal Cancer Survival

Delaying adjuvant chemotherapy for more than 6 weeks post colorectal cancer surgery is associated with worse disease-free survival in high-risk stage II and III patients. A study of 5719 individuals revealed a 5-year disease-free survival of 78.0% vs. 73.2% in early vs. late-start groups, respectively. Those initiating chemotherapy later had a hazard ratio of 1.24 for worse outcomes. No significant difference in adverse events was observed between the groups.

Journal Article by Gögenur M, Rosen AW (…) Holländer NH et 29 al. in JAMA Surg

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