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Endoscopic Ultrasound for Acute Cholecystitis Shows Strong Results

EUS-guided gallbladder drainage is a viable option for high-risk patients with acute cholecystitis, offering both safety and effectiveness.

  • Technical and clinical success rates were high at 95.8%.
  • The study analyzed data from 701 patients across 18 studies with over a year of follow-up.

Surgeons can consider EUS-GBD as a first-line treatment for patients unfit for surgery, given its low adverse event rates.

  • This approach offers a durable solution with minimal complications.

Review by Canakis A, Tugarinov N (…) Baron TH et 9 al. in Gastrointest Endosc

Copyright © 2025 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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Endoscopic Pyloromyotomy Outperforms Laparoscopic Stimulation for Gastroparesis

Endoscopic peroral pyloromyotomy (pop/g-poem) shows superior outcomes compared to laparoscopic gastric electrical stimulation (ges) for treating medically refractory gastroparesis.

  • Mean operative time was significantly shorter for pop/g-poem (28.9 minutes vs 95.6 minutes, p < 0.001).
  • Length of stay was reduced with pop/g-poem (0.5 days vs 2.4 days, p < 0.001) and it had a lower symptom recurrence rate (41.6% vs 78.8%, p < 0.001).

Consider pop/g-poem as the first-line surgical option for better efficacy and reduced morbidity in gastroparesis patients.

Comparative Study by Shim SH, Cheng J (…) El-Hayek KM et 7 al. in J Am Coll Surg

Copyright © 2025 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Transforming Rectal Cancer Care: Upfront Surgery Wins

Selected rectal cancer patients can safely skip neoadjuvant therapy and proceed directly to total mesorectal excision.

  • Among 94 patients, 100% had local recurrence-free survival at 3 years; 97% at 5 years.
  • R0 resection achieved in 99%, leading to substantial overall survival rates of 97% at 3 years and 95% at 5 years.

This evidence supports refining patient selection for surgery, minimizing unnecessary preoperative treatment while maintaining excellent outcomes.

  • 87% distant metastasis-free survival at 3 years; 81% at 5 years underscores the effectiveness of this approach.

Video-Audio Media by Fernandez LM, Moreira Azevedo J (…) Parvaiz A et 5 al. in Dis Colon Rectum

Copyright © The ASCRS 2025.

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Predicting Post-Hepatectomy Liver Failure with Machine Learning

A new machine learning model improves prediction of liver failure after major hepatectomy, enhancing surgical decision-making.

  • The pilot model achieved AUCs as high as 0.904, significantly outperforming traditional models (AUCs 0.502-0.644).
  • The model integrates 55 variables, including novel biomarkers, across preoperative, intraoperative, and postoperative datasets.

This innovation allows surgeons to identify high-risk patients within hours of surgery, enabling tailored perioperative strategies.

  • Early risk stratification could reduce morbidity and improve outcomes in liver surgery patients.

Journal Article by Shen H, Yuan T (…) Li J et 18 al. in EClinicalMedicine

© 2025 The Author(s).

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Diminished Infection Rates with Biodegradable Temporizing Matrix

Using a biodegradable temporizing matrix (BTM) can lead to low infection rates in complex wounds, changing how surgeons approach non-graftable cases.

  • Only 14% of patients in a diverse cohort of 22 experienced clinical infection after BTM application.
  • Microbial growth was found in 76% of pre-BTM swabs, but this did not correlate with infection rates post-application.
  • Salvage methods were effective, with 66% of infected patients successfully retaining BTM.

Surgeons can confidently use BTM, knowing most patients will achieve complete wound healing despite initial microbial concerns.

Journal Article by Wilson S, Muscat E (…) Wearn C et 2 al. in JPRAS Open

© 2025 The Authors. Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons.

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Robotic Hepatectomy Surpasses Laparoscopy for Liver Cancer

Robotic hepatectomy enhances surgical options for high-risk liver cancer patients with comparable oncologic outcomes to laparoscopic methods.

  • Robotic techniques show similar length of hospital stay and complication rates to laparoscopic approaches but may offer better precision.
  • Patients experience shorter recovery times and can start adjuvant therapy sooner.

Surgeons should consider robotic hepatectomy as a viable option for complex cases in hepatocellular carcinoma, despite the learning curve.

  • A team-based surgical approach can help mitigate challenges in mastering robotic techniques.

Review by Haugen CE, Llore N and Hawksworth JS in Ann Surg Oncol

© 2025. Society of Surgical Oncology.

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Surgical Resection Reduces Sigmoid Volvulus Recurrence

Resection significantly lowers recurrence in sigmoid volvulus but comes with increased mortality risks.

  • Resection reduced recurrence rates to 12% compared to 69% in non-resection (NNT 6).
  • Mortality increased by 69% with resection, necessitating careful patient selection (NNH 17).

In non-gangrenous cases, resection prevents recurrence with no significant mortality increase.

  • Optimizing patient selection and perioperative care is crucial for improved outcomes.

Systematic Review by Jiang X, Guo S and Yang L in Langenbecks Arch Surg

© 2025. The Author(s).

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Endoscopic submucosal dissection outperforms mucosal resection for early gastric cancer.

  • ESD achieved a fourfold increase in both en bloc and curative resection rates compared to EMR.
  • Favorable outcomes were particularly noted in differentiated lesions and during long-term follow-up.

Consider ESD as the preferred method for selected early gastric cancer patients, keeping in mind the need for advanced skills and longer procedure times.

  • The analysis included nine studies with 3,574 patients, providing robust evidence for this approach.

Systematic Review by Zheng X and Xu L in Front Med (Lausanne)

Copyright © 2025 Zheng and Xu.

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Enhanced Recovery Nursing Model Cuts Hospital Stay for Gastric Cancer

Gastric cancer patients benefit significantly from an enhanced recovery nursing model during the perioperative period.

  • Postoperative stay was 7.2 days in the new model vs. 10.5 days with traditional care (p < 0.001).
  • Complications occurred in only 10% of patients using the new model compared to 26.7% in the control group (p = 0.013).
  • Time to first flatus was reduced by over 12 hours, and patient satisfaction soared (92.5 vs. 80.2 points, p < 0.001).

Consider adopting this model to enhance recovery and outcomes in your gastric cancer surgery practice.

Observational Study by Song Y, Zhao Y (…) Liao X et 2 al. in Medicine (Baltimore)

Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc.

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Dietary Questionnaire Validates Nutritional Recovery in Gastric Cancer Surgery

A new dietary questionnaire effectively tracks nutritional status post-gastrectomy for gastric cancer.

  • Dietary volume intake drops to 39.7% one month after surgery, rebounding to 74.8% by one year (p < .001).
  • Significant correlation found between dietary volume and caloric intake (r = 0.299-0.599) and weight loss (r = -0.119 to -0.301).

This tool can help surgeons identify at-risk patients and tailor nutritional interventions for better outcomes.

  • Nutritional risk scores peaked at one month but improved with time, emphasizing the need for early dietary support.

Observational Study by Kim TH, Park JH (…) Jeong SH et 5 al. in Medicine (Baltimore)

Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc.

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