Hepatic vein occlusion with portal vein embolization significantly boosts future liver remnant growth in 2-stage hepatectomies, impacting patient selection and stage feasibility.

• Hepatic vein occlusion combined with portal vein embolization led to a 36.8% increase in future liver remnant, 24.5% higher than portal vein embolization alone (p < .01).
• Associating liver partition and portal vein ligation resulted in a 68.5% future liver remnant increase and a 95% feasibility rate for stage 2.

Surgeons should consider these strategies for optimal liver regeneration planning in patients.

• Morbidity and mortality rates were similar among approaches, highlighting their safety profiles.

Surgical resection significantly increases cure probabilities for pancreatic ductal adenocarcinoma.

• Cure probability for patients undergoing resection is 25.24%, compared to 6.82% for those who do not.
• Neoadjuvant chemotherapy before surgery improves cure rates (30.0% vs 17.05% with upfront surgery).

Earlier detection and combined treatment strategies are crucial for improving long-term outcomes.

• Cure probabilities decrease with older age and advanced clinical stage, underscoring the need for timely intervention.

Surgically resected early-onset pancreatic cancer shows worse outcomes and aggressive molecular features compared to late-onset cases.

• Patients under 50 had a median disease-free survival of 10.9 months versus 14.2 months for those 50 and older (p = 0.011).
• More young patients received adjuvant chemotherapy, yet their disease-free survival was shorter at 12.6 months vs. 16.0 months (p = 0.022).

Surgeons should consider aggressive monitoring and tailored treatment strategies for younger pancreatic cancer patients due to these poorer outcomes.

• Early-onset cases show increased genes for aggressive pathology, including S100A2 and TP63.

Pancreaticoduodenectomy is feasible in patients with complete situs inversus, ensuring oncologic principles are upheld.

• Complete R0 resection achieved in a 68-year-old with pancreatic adenocarcinoma.
• Complicated course included grade II adverse events with a 16-day hospital stay.

Surgeons should prioritize meticulous preoperative planning and adapt intraoperatively to unique anatomical variations.

• Final pathology revealed high-stage disease with 30 positive lymph nodes out of 33 examined.

Early protocol CT scans in high-risk patients after pancreatoduodenectomy increase detection of complications but don’t improve overall outcomes.

• In a prospective cohort, 76.7% of asymptomatic patients received CT scans by day 4 versus day 8 in historical controls.
• Abnormal findings were noted in 73.9% of scans, leading to timely intervention in 6 patients.

Despite increased interventions, there were no changes in hospital stay or 90-day mortality.

• Clinically relevant scores ≥5 correlated strongly with progression to significant complications (72.7% vs 41.1%; p< .001).

A new standardized robotic dissection technique for the celiac axis and hepatic artery shows promise for safer, more precise pancreatic surgery.

• Successfully performed level 1 to level 3 dissection with no intraoperative arterial injury.
• Utilized advanced imaging for stable magnified visualization, improving safety during intricate dissections.

This approach supports consistent oncological principles in robotic procedures.

• Emphasizes selective instrument use to minimize thermal and mechanical injury during dissection.