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SF-BARI Score as a Standard Tool for Metabolic Bariatric Surgery Outcomes

Researchers analyzed data from two randomized clinical trials to assess the feasibility of using the Swiss-Finnish Bariatric Metabolic Outcome Score (SF-BARI score) as a standardized tool for measuring outcomes in metabolic bariatric surgery (MBS). They found that the SF-BARI score, which includes measures of weight loss, comorbidities, complications, and quality of life, was correlated with other outcome measures and demonstrated differences between surgical procedures and over time. These findings suggest that the SF-BARI score is a simple and relevant tool for defining and measuring MBS outcomes.

Journal Article by Peterli R, Hurme S (…) Salminen P et 3 al. in JAMA Surg

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Improved Survival Associated with Resection in Localized Pancreatic Neuroendocrine Carcinoma

A retrospective study of 199 patients with localized small- and large-cell pancreatic neuroendocrine carcinoma (pannec) found that resection was associated with improved overall survival, while adjuvant chemotherapy did not significantly impact survival. The study also revealed an increasing trend in the rates of resection and adjuvant treatment since 2011. Resected patients were younger, treated more often at academic institutions, had more distal tumors, and a lower number of small-cell pannec. These findings highlight the potential benefit of resection in managing localized pannec, while suggesting the need for further investigation into the role of adjuvant chemotherapy.

Journal Article by Sugawara T, Rodriguez Franco S (…) Schulick RD et 4 al. in J Am Coll Surg

Copyright © 2023 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Operationalizing Value Congruence for Improved Well-Being in General Surgery Residency

The study investigated the impact of value congruence (vc) on well-being and job retention among general surgery residents. Survey #1 revealed a lack of vc, with themes of inaccessibility, inconsiderateness, inauthenticity, and insufficiency of well-being resources. Program directors had varying awareness and alignment with these perceptions. Survey #2 showed that higher vc was significantly associated with increased flourishing. The findings highlight the need for open dialogue and institutional actions to address the perceived lack of vc and optimize well-being in surgical residency programs.

Journal Article by Cevallos JR, Gonzales PA (…) Lebares CC et 2 al. in J Am Coll Surg

Copyright © 2023 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Successful patient-derived xenograft engraftment predicts recurrence and survival in pancreaticobiliary cancer

Researchers evaluated the correlation between successful patient-derived xenograft (PDX) engraftment and survival in pancreaticobiliary cancer. They implanted 384 PDX models and found a 41% engraftment rate. Successful engraftment was strongly associated with both recurrence-free survival and overall survival outcomes. Furthermore, successful PDX tumor generation occurred significantly earlier than clinical recurrences. These findings suggest that successful PDX models can predict recurrence and survival across tumor types and may provide crucial lead time to modify surveillance or treatment plans before cancer recurrence.

Journal Article by Lynch IT, Abdelrahman AM (…) Truty MJ et 4 al. in J Am Coll Surg

Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American College of Surgeons.

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Long-Term Benefits of Diaphragm Plication Surgery

Patients who underwent open or robotic-assisted transthoracic diaphragm plication for diaphragm paralysis and eventration reported significant improvement in dyspnea and fatigue symptoms, as well as improved overall quality of life and exercise capacity. The majority of patients would recommend the surgery to others. There were no significant differences in symptom improvement or quality of life responses between the open and robotic-assisted approaches.

Journal Article by Hunt AR, Stuart CM (…) Wojcik BM et 8 al. in J Am Coll Surg

Copyright © 2023 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Racial, Socioeconomic, and Insurance Disparities in Colon Cancer Care and Outcomes

Disparities in colon cancer care and outcomes exist based on race/ethnicity, socioeconomic status (SES), and insurance. Low-performing hospitals treat more non-Hispanic black, Hispanic, low SES, and Medicaid patients. Patients with low SES and Medicaid have decreased odds of receiving high-quality care at low-performing hospitals, while non-Hispanic black patients have decreased odds at high-performing hospitals. Low SES, Medicare, Medicaid, and uninsured patients have worse overall survival at both low- and high-performing hospitals. It is important to improve low-performing hospitals and identify mechanisms contributing to survival disparities.

Journal Article by Buchheit JT, Silver CM (…) Merkow RP et 4 al. in Ann Surg Oncol

© 2023. Society of Surgical Oncology.

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Indocyanine Green Fluorescence Imaging Has No Impact on Mid-Term Outcomes of Laparoscopic Right-Sided Colectomy

In a retrospective cohort study, researchers evaluated the mid-term outcomes of indocyanine green fluorescence imaging-guided laparoscopic right-sided colectomy. After propensity score matching, they found that the number of dissected central, intermediate, and total lymph nodes was significantly higher in the indocyanine green group. However, there was no difference in the 3-year relapse-free survival and overall survival rates between indocyanine green and non-indocyanine green groups. Thus, the study suggests that indocyanine green fluorescence imaging does not impact mid-term outcomes of laparoscopic right-sided colectomy.

Journal Article by Daibo S, Watanabe J (…) Endo I et 5 al. in Dis Colon Rectum

Copyright © The ASCRS 2023.

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Local Regrowth in Rectal Cancer After Watch-and-Wait Strategy Signals Higher Distant Metastasis Odds Than Upfront Surgery

A retrospective multicenter study compared the risk of distant metastases in rectal cancer patients who achieved a clinical complete response followed by local regrowth with those managed by surgery after chemoradiation. Out of 79 patients with local regrowth, 21 developed distant metastases, whereas only 10 out of 74 patients in the upfront surgery group had distant metastases. Local regrowth and final pathology were identified as independent risk factors associated with distant metastases. The study highlights the higher risk of distant metastases in patients with local regrowth after watch-and-wait therapy.

Journal Article by São Julião GP, Fernández LM (…) Perez RO et 10 al. in Dis Colon Rectum

Copyright © The ASCRS 2023.

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Stump Length Is the Most Significant Factor for Rectal Stump Leakage

Rectal stump leakage is a significant complication after discontinuity resection, with a rate of 11.78% in this study. The risk varies depending on the surgical procedure, and it was highest after subtotal pelvic exenteration. Researchers found that a shorter rectal stump, previous pelvic radiotherapy, chemotherapy, and previous laparotomy were independent risk factors for rectal stump leakage. The study highlights the importance of considering these risk factors in surgical decision-making to prevent rectal stump leakage and the subsequent need for invasive treatment and extended hospitalization.

Journal Article by Ritter AS, Dumm N (…) Schneider M et 4 al. in Dis Colon Rectum

Copyright © The ASCRS 2023.

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Genomic and clinicopathologic characteristics of small bowel adenocarcinoma

The study examined 68 surgical resections from patients with small bowel adenocarcinoma (SBA) to investigate the correlation between immunophenotypes, DNA mismatch repair status, genomic profiling, and clinicopathologic characteristics. The results showed that the expression of certain proteins correlated with tumor location, histologic type, and TNM stage. Muc1 and muc4 expression were associated with worse prognosis, while muc2 expression correlated with better prognosis. Gastric-type SBA exhibited distinct molecular pathways compared to intestinal-type SBA. These findings provide insights into the genomic and clinicopathologic characteristics of SBA.

Journal Article by Hoshimoto A, Tatsuguchi A (…) Iwakiri K et 12 al. in Am J Surg Pathol

Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.

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