A study investigated the use of a fut variant-based CA19-9 tumor marker gene test to assess the outcome of pancreatic cancer surgery. The test showed that higher preoperative CA19-9 levels were associated with recurrence and mortality in patients with higher fut groups, but not in lower fut groups. CA19-9 levels after neoadjuvant therapy and normalization […]

Myosteatosis and creatinine-to-cystatin C ratio (CCR) were evaluated as prognostic biomarkers in patients with pancreatic cancer (PC) who underwent radical surgery. The study included 215 patients, and the results showed that myosteatosis and CCR ≤ 1.09 were independent risk factors associated with poor overall survival (OS) and disease-free survival (DFS). Furthermore, patients with the combination […]

The study compared the response to neoadjuvant chemotherapy and overall survival in patients with invasive intraductal papillary mucinous neoplasm (i-ipmn) and de novo pancreatic ductal adenocarcinoma (pdac). The results showed that i-ipmn histology was independently associated with a lower risk of recurrence and death. Pathological, radiological, and positron emission tomography responses to neoadjuvant therapy were […]

The study presents the successful use of left hepatectomy combined with right hepatic artery reconstruction for treating hilar cholangiocarcinoma. A 60-year-old male patient with obstructive jaundice underwent the procedure, which involved resection of the right hepatic artery invaded by tumors, lymphadenectomy, and hepaticojejunostomy. The operation was completed in 345 minutes with minimal bleeding, and the […]

Researchers present the first-ever full robotic surgical step-by-step technique for treating perihilar cholangiocarcinoma, a challenging procedure. This innovative approach allows for better dissection and suture due to the flexible and accurate movements of the robotic instruments, overcoming the limitations of laparoscopic techniques. The study showcases the successful performance of an extended right hemihepatectomy for perihilar […]

Frail patients with pancreatic cancer who underwent minimally invasive pancreaticoduodenectomy had improved postoperative outcomes compared to open surgery, according to a study. The analysis of pancreaticoduodenectomy cases for pancreatic ductal adenocarcinoma revealed lower rates of complications, major morbidity, and nonhome discharge for those who underwent minimally invasive procedures. Robotic surgery had even better outcomes than […]

A propensity score-matched analysis compared the outcomes of laparoscopic pancreaticoduodenectomy (LPD) and open pancreaticoduodenectomy (OPD). LPD showed longer operative times, reduced blood loss, higher rates of pancreatic fistula and delayed gastric emptying, while postpancreatectomy hemorrhage, major morbidity, mortality, hospital stay, and readmissions were not significantly different. LPD was associated with higher intensive care use and […]

Grade-C postoperative pancreatic fistulas (POPfs) following pancreaticoduodenectomy are serious complications associated with high morbidity and mortality rates. Researchers analyzed a national database of 26,552 patients who underwent this surgery and found that 1.2% of patients suffered from grade-C POPfs, while the rate of grade-B POPfs significantly increased over time. Grade-C POPfs were associated with several […]

A meta-analysis examined the clinical features and prevalence of annular pancreas (AP), a rare gastrointestinal congenital malformation. Analysis of 12,729,118 patients found a pooled prevalence of AP at 0.0045%. The most common comorbidity in adults and children with AP was duodenal obstruction, with pooled prevalence rates of 24.04% and 52.58%, respectively. The predominant surgical procedure […]