Robotic duodenum-preserving pancreatic head resection (DPPHR) utilizing video-based indocyanine green fluorescence imaging was successfully performed on a 48-year-old patient with pancreatic duct stones and chronic pancreatitis. The surgery lasted 265 minutes with minimal blood loss. Postoperative pathology confirmed the diagnoses, and the patient was discharged without complications after 13 days. This technique, employed in four […]
Category: HPB & Spleen
Implications of precursor lesions and early cancerous changes in the gallbladder and bile ducts
The study explores terminology, classification, and significance of dysplasia and early carcinoma in the gallbladder and bile ducts. Most precursor lesions and early cancerous changes are clinically undetectable. Low-grade dysplasia is challenging to define and lacks clinical significance, but additional sampling is required to exclude significant lesions. High-grade dysplasia (carcinoma in situ) necessitates complete sampling […]
Presence of Enterococcus spp. in the Upper Gastrointestinal Tract is a Risk Factor for Mortality in Pancreatic Cancer Surgery
A recent study conducted at a German pancreatic center investigated the role of microbiota in perioperative outcomes of pancreatic head resections. The study utilized 16s rrna sequencing and microbial culturing to analyze samples collected from various gastrointestinal sites of 101 patients undergoing surgery. The findings revealed that the presence of Enterococcus spp. in the upper […]
Gad2 immunohistochemistry is a highly specific diagnostic tool for identifying pancreatic origin in neuroendocrine neoplasms
Researchers analyzed a large number of tissue samples and found that gad2 immunohistochemistry is a highly specific diagnostic marker for neuroendocrine neoplasms of the pancreas. The expression of gad2 was only observed in a few normal cell types, making it a potential diagnostic tool. It was found to be most commonly seen in neuroendocrine carcinomas […]
Long-term Consequences of Necrotising Pancreatitis: Burden of Recurrent Disease, Interventions, and Insufficiency
The long-term consequences of necrotising pancreatitis, including complications, interventions, and quality of life, were assessed in a follow-up study of 373 patients. Results showed that 26% of patients were readmitted for recurrent pancreatitis, 13% received endoscopic or percutaneous drainage, and 8% underwent pancreatic necrosectomy or surgery. Endocrine and exocrine insufficiency developed less frequently in patients […]
Improved Localization and Complete Resection in Pancreatic Hypoglycemia Using Intraoperative Segmental Pancreatic Occlusion and Insulin Assay
Combining intraoperative segmental pancreatic occlusion and insulin assays significantly enhances the localization and complete resection of hypersecretory pancreatic tissues in patients with pancreatic hypoglycemia. A retrospective analysis of 11 cases showed that the insulin assay, performed 30 minutes post-resection, accurately located target tissues and achieved a complete resection rate of 100%. Intraoperative blood glucose monitoring, […]
Portal Vein Resection in Pancreatic Neuroendocrine Neoplasms
Portal vein resection in surgery for pancreatic neuroendocrine neoplasms was analyzed in this study. Among 666 patients, 8% underwent portal vein resection. Postoperative complications were comparable to standard resection, with a low 90-day mortality rate. Radical resection resulted in excellent 5-year overall and disease-specific survival rates. This study provides valuable data on the perioperative and […]
Predictors of Persistent Pain after Extracorporeal Shockwave Lithotripsy for Chronic Pancreatitis
The study aimed to identify the predictors of persistent pain in patients with chronic calcific pancreatitis following extracorporeal shockwave lithotripsy (ESWL). A total of 640 patients were assessed, and 68% experienced pain relief after ESWL while 32% had persistent pain. Predictors of persistent pain included alcohol and tobacco consumption, longer duration of symptoms, dilated main […]
The Geriatric Nutritional Risk Index is a Prognostic Indicator in Intrahepatic Cholangiocarcinoma Patients undergoing Hepatectomy
In a retrospective cohort study of 123 patients with intrahepatic cholangiocarcinoma (ICC) who underwent curative surgery, researchers investigated the prognostic value of the Geriatric Nutritional Risk Index (GNRI). Patients with low GNRI scores had significantly poorer outcomes in terms of recurrence-free survival (RFS) and overall survival (OS) compared to those with high GNRI scores. Lymph […]
Improved neoadjuvant and adjuvant therapy needed for biliary tract cancer
Neoadjuvant and adjuvant therapy for biliary tract cancer (BTC) have shown limited success in improving outcomes for patients. This review highlights that while a minority of BTC patients are eligible for curative surgery, their survival rates remain poor with high recurrence rates. The study evaluates current clinical trials and identifies challenges and limitations in their […]