Increased lymph node yield (LNY) of 22 or more nodes is linked to better overall survival (OS) and longer time to recurrence (TTR) in node-negative pancreatic ductal adenocarcinoma (PDAC) patients receiving neoadjuvant therapy (NAT). This association was observed in two separate patient cohorts, highlighting the importance of LNY in predicting oncologic outcomes and suggesting potential […]
Category: HPB & Spleen
Robotic Pancreatoduodenectomy: Experience Matters
Robotic pancreatoduodenectomy showed decreased complications and increased efficiency with experience, as seen in 150 consecutive patients. Morbidity was lower, mortality rates were comparable, and operative times significantly reduced in the latter half of cases. Higher lymph node resection and more partial portal vein resections were observed in experienced cases. These results emphasize the safety and […]
New Scoring System Predicts Survival in Recurrent Hepatocellular Carcinoma
The albumin-bilirubin-alpha-fetoprotein (ALB-AFP) score effectively predicts survival in patients with recurrent hepatocellular carcinoma undergoing repeat hepatectomy. By combining albumin-bilirubin grading and serum alpha-fetoprotein levels, researchers stratified patients into three groups, revealing significant differences in 5-year recurrence-free survival: 22.4%, 20.7%, and 0.0%. The ALB-AFP score demonstrated superior predictive value for survival compared to the Japan Integrated […]
ERAS Protocols Improve Outcomes and Cost-Efficiency in Minimally Invasive Liver Surgery
Enhanced Recovery after Surgery (ERAS) recommendations in minimal invasive liver surgery significantly reduce postoperative complications by 14% and prove cost-effective by offsetting the expenses associated with complications. Complications greater than Clavien-Dindo grade II incur the highest costs, reducing profit margins by a median of € 6,640. Embracing ERAS society recommendations in liver surgery leads to […]
Heparin reduces risk of posthepatectomy liver failure
Heparin was found to significantly reduce the risk of posthepatectomy liver failure in patients who underwent liver cancer hepatectomy. A study of 1388 patients showed that heparin administration was associated with a decreased occurrence of liver failure, indicating its potential as a preventive option. Statistical analysis demonstrated a significant association between heparin treatment and reduced […]
CA 19-9 Surveillance Enhances Survival in Resected Ampullary Cancers
CA 19-9 surveillance in resected ampullary cancers significantly improves survival rates by detecting recurrences early. Among 572 patients, a rise in CA 19-9 levels predicted recurrences accurately, with a serial increase proving to be a more reliable indicator. The optimal threshold for identifying a recurrence was established, leading to prompt detection and treatment. Patients with […]
Step-up Approach Proves Effective in Treating Infected Necrotizing Pancreatitis
Real-life data from a single center experience show that the “step-up” approach for treating infected necrotizing pancreatitis is feasible, with an 80.5% success rate in resolving infections. The strategy had mild morbidity, a 19.5% mortality rate at 6 months, and led to long-term sequels in some patients (exocrine pancreatic insufficiency, diabetes, pancreatic fistula, parietal hernia). […]
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