Researchers analyzed data from 2020 to 2040 to understand the trends in pancreatic cancer (PC) incidence and mortality worldwide. PC is linked to higher socioeconomic status, with Asia, especially China, bearing the greatest burden. Among age groups, those aged 65 and older are most affected, except in countries with medium and low human development indices […]

Researchers investigated the volumetric changes in the left liver after right hepatectomy and the factors influencing the degree of hypertrophy and severe post-hepatectomy liver failure (PHLF). After right hepatectomy, the left liver remnant exhibited a 25% hypertrophy with varying growth rates. Factors like gender, middle hepatic vein resection, and standardized future liver remnant influenced hypertrophy. […]

This study delves into the use of allogeneic vessels (AV) in pancreaticoduodenectomy (PD) with portal vein resection (PVR) and its relationship with portal vein thrombosis (PVT). The findings reveal that PVT is notably prevalent, especially in cases involving AV reconstructions. Independent risk factors for PVT include diabetes, the surgical procedure performed, and AV reconstruction. Furthermore, […]

This study delves into pancreatic cancer outcomes in the disaggregated Asian American, Native Hawaiian, and Pacific Islander (AANHPI) population, which is often underrepresented in scientific research. Analyzing data from 296,448 patients, it reveals that AANHPI patients, as a whole, exhibited better median survival than Caucasians and African Americans. Notably, survival rates varied among AANHPI subpopulations, […]

This groundbreaking study analyzed the outcomes of robotic hepatectomy for five major malignant liver diseases. Among the 210 patients who underwent this procedure, including cases like colorectal liver metastases and hepatocellular carcinoma, the results were promising. A favorable 5-year overall survival benefit was observed across these disease processes. The robotic platform demonstrated its prowess in […]

In a randomized clinical trial, researchers compared laparoscopic and open pancreaticoduodenectomy for patients with pancreatic ductal adenocarcinoma. The study found that, despite longer operative times, laparoscopic procedures led to less blood loss. Both groups had similar 90-day mortality, rates of complications, and postoperative length of stay. The results suggest that laparoscopic pancreaticoduodenectomy, when performed by […]

Researchers examined the post-recurrence progression in patients with resected pancreatic ductal adenocarcinoma (PDAC) and the implications for treatment. Most PDAC patients experience recurrence within two years, with varying survival outcomes depending on the site of recurrence. Lung recurrence showed significantly longer post-recurrence survival. A subset of patients with local-only recurrence, especially those with specific markers […]

An international multicenter study analyzed 459 patients who underwent pancreatic resection for adenocarcinoma originating from intraductal papillary mucinous neoplasia (IPMN). Results showed that recurrence was common, with 45.5% experiencing it, including 23.2% with early recurrence within a year. Treatment of recurrence, such as adjuvant chemotherapy and other modalities, significantly improved overall survival, with a median […]

Researchers in southwestern China developed a predictive tool called a nomogram to help identify patients with hepatocellular carcinoma (HCC) who are at risk of experiencing moderate-to-severe complications after hepatectomy surgery. The nomogram uses six variables, including diabetes and the extent of liver resection, to estimate the risk of postoperative complications in HCC patients. This tool […]