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Inside stent placement for preoperative biliary drainage in perihilar cholangiocarcinoma patients showed significantly lower rates of recurrent biliary obstruction, longer stent patency, fewer replacements, and reduced hospital stays and costs compared to conventional stent placement. Additionally, inside stent placement resulted in fewer complications and lower…
High intratumoural tertiary lymphoid structure (TLS) score correlated with prolonged survival, while high TLS density in adjacent tissue indicated worse prognosis in combined hepatocellular-cholangiocarcinoma. Mature TLSS linked to favorable outcomes with more CD8+ T cell infiltration. TLSS distribution and density can predict prognosis and serve…
Novel HARO-ALPPS procedure significantly restricts hepatic artery blood supply post-surgery, enhancing liver regeneration in HCC patients with severe fibrosis. Results show superior outcomes in terms of mortality and liver function compared to conventional ALPPS procedure. Further studies required to confirm oncologic benefits of HARO-ALPPS in…
Effective local palliative treatment of intraductal papillary neoplasm of the bile duct using percutaneous transhepatic cholangioscopy-assisted biliary polypectomy. Feasible, safe, and successful in five patients, with technical and therapeutic success achieved. Patients with mucin-hypersecreting cast-like or polypoid type tumors benefited, with no serious adverse events.…
3D imaging challenges traditional size-based classification of precancerous lesions in pancreatic ductal adenocarcinoma. Over 1400 lesions meeting size criteria for pancreatic intraepithelial neoplasia (PanIN) were identified in 3D analysis, with a quarter digitally sectioning as intraductal papillary mucinous neoplasms (IPMN). Half of these large lesions…
TRIANGLE operation, combined with adequate adjuvant chemotherapy, can improve the prognosis of pancreatic head cancer. The triangle operation is safe for PDAC patients undergoing PD, reduces local recurrence rates, and may enhance patient survival with proper adjuvant chemotherapy support, according to a retrospective study. This…
Increases and decreases in liver stiffness measurements independently predict liver-related events in NAFLD. Progression to higher stiffness levels was linked to a higher risk of liver events, while regression to lower levels decreased this risk. These findings highlight the clinical significance of monitoring liver stiffness…
Arterial coverage with retromesenteric omental flap significantly reduces clinically relevant postpancreatectomy hemorrhage after pancreaticoduodenectomy. This novel technique, compared to no coverage, led to lower hemorrhage rates, fewer postoperative pancreatic fistulas, and decreased reoperation needs. Multivariate analysis confirmed the omental flap as an independent protective factor…
Spontaneous rupture of hepatocellular carcinoma (RHCC) poses a major threat, with mortality rates ranging from 25-75%. Recent research highlights improved survival rates and reduced complications through a treatment combination of transcatheter arterial embolization/chemoembolization (TAE/TACE) followed by elective hepatectomy. Active surveillance efforts, advanced diagnostic tools, and…
Minimally invasive robotic right hepatectomy with en bloc caudatectomy is safe and feasible for Bismuth IIIa hilar cholangiocarcinoma, with successful outcomes and minimal complications. The technique allows for radical resections and satisfactory postoperative recoveries, demonstrating a new surgical approach for challenging hepatic conditions. This approach…
