Researchers conducted a retrospective review of 394 microwave ablation (MWA) procedures on 328 patients with colorectal liver metastasis. The study found a low morbidity rate, with Clavien-Dindo grade III or IV complications occurring in 3.6% of patients, all of whom had concomitant procedures. Incomplete ablation and local recurrence rates were 1.5% and 6.3% per tumor, […]
Category: HPB & Spleen
Regional Metastasis Worsens Survival in Nonfunctional Pancreatic Neuroendocrine Tumors
Lymph node metastasis (LNM) in nonfunctional pancreatic neuroendocrine tumors (NF-PNET) has a negative impact on disease-free survival (DFS) and overall survival (OS). In a systematic review of 52 studies involving 24,608 PNET cases, reported LNM rates for NF-PNET ranged from 7% to 64%, with higher rates in tumors >2 cm. Additionally, 66% of the studies […]
CA19-9 and DUPAN-2 Combination Identifies Early-Stage Pancreatic Adenocarcinoma
Patients with pancreatic ductal adenocarcinoma (PDAC) and normal levels of CA19-9 and DUPAN-2 are more likely to have resectable and early-stage cancer. In a study of 521 patients, those with normal CA19-9 and DUPAN-2 had a significantly higher proportion of resectable PDAC (71.5%) and a 5-year survival rate of 66.0%, much better than other groups […]
Significant Variability in Managing Malignant Gastric Outlet Obstruction in Pancreatic Cancer, with Rising Use of EUS-Gastrojejunostomy
Survey of 290 pancreatologists revealed significant differences in managing malignant gastric outlet obstruction (MGOO) due to pancreatic cancer. Endoscopic stenting (ES) was most common, but EUS-Gastrojejunostomy (EUS-GJ) adoption is increasing. Decision drivers include life expectancy and patient frailty, with lack of standardized algorithms. Availability of EUS-GJ remains suboptimal, attributed to the steep learning curve. Journal […]
Nomogram Predicts Survival in Lymph Node-Negative Hepatocellular Carcinoma
Clinicians developed a nomogram to predict cancer-specific survival (CSS) in hepatocellular carcinoma (HCC) patients without lymph node metastasis (LNM), achieving high accuracy in both internal and external validation. Analysis of 6,840 HCC patients revealed age, gender, bone metastasis, lung metastasis, AFP, T stage, surgery, and chemotherapy as significant prognostic factors. The nomogram’s concordance index (C-index) […]
Straight Stomach Reconstruction Reduces Delayed Gastric Emptying After Pancreaticoduodenectomy
Clinicians found that anchored straight stomach reconstruction (SSR) significantly reduces the incidence of delayed gastric emptying (DGE) after pancreaticoduodenectomy (PD), also leading to improved postoperative nutritional recovery. A case series analysis of 125 PD patients showed that those in the SSR group had a DGE rate of 13%, compared to 33% in the non-SSR group. […]
Pancreas-Preserving Duodenectomy Achieves High Resection Rates with Lower Complications
Pancreas-preserving duodenectomy (PPrD) achieved an R0 resection rate of 93% among patients treated for duodenal neoplasms. In a retrospective cohort of 29 patients, postoperative complications occurred in 34.4% of cases, with 13.7% at Clavien-Dindo grade III-V. PPrD had lower rates of pancreatic leak, delayed gastric emptying, and deep surgical site infection compared to pancreaticoduodenectomy. This […]
Malpractice Claims Following Major Liver and Pancreatic Surgeries
General surgery is a highly litigious specialty, with most claims related to delays in diagnosis or surgical negligence. A study analyzing malpractice cases from the last two decades found that the majority named surgeons as defendants, with a higher likelihood of verdicts favoring defendants. Payouts to plaintiffs, though less common, were significant, highlighting the legal […]
Hidden Port Site Incision for Robotic Foregut and Hepatopancreatobiliary Operation
Developed to minimize visible scars on the abdomen, the hidden port site incision technique at the pubic hairline offers a cosmetically superior approach for common foregut and hepatopancreatobiliary procedures. This technique maximizes cosmetic outcomes while maintaining clinical efficacy, especially beneficial for patients with poor healing or scarring tendencies. Journal Article by Fefferman ML, Zheng C, […]
Camrelizumab and Radiotherapy for Unresectable Intrahepatic Cholangiocarcinoma Show Promise in First-Line Therapy
External radiotherapy plus camrelizumab as first-line therapy for unresectable intrahepatic cholangiocarcinoma demonstrated a 1-year progression-free survival rate of 44.4% and antitumor activity with low toxicity levels. The objective response rate was 61.1% and the disease control rate was 86.1%. Further investigation is warranted for this promising treatment approach. Journal Article by Zhu M, Jin M […]