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J Gastrointest Surg26 May 2024

Temporal Disparities in Curative-Intent HCC Treatment Utilization

Racial and socioeconomic disparities impact access to curative treatments for hepatocellular carcinoma (HCC). African-American and Hispanic patients had lower odds of receiving ablative therapy and surgical resection compared to whites, while disparities in liver transplantation varied. While trends improved for white and API/other patients, African-American…

Dig Liver Dis26 May 2024

Effectiveness of Lumen-Apposing Metal Stents for Benign Biliary Strictures

Lumen-apposing metal stents (LAMS) show promising results for treating short benign biliary strictures, with a high technical success rate of 100% and a clinical success rate of 85.7%. Adverse events, including stent migration, were found in 17.1% of patients, and stricture recurrence occurred in 18.5%…

J Gastrointest Oncol25 May 2024

Identification of Early Detection Biomarkers for Pancreatic Cancer

Metabolomics analysis identified indoleacetate, 3-hydroxydecanoate, and retention index as top candidate biomarkers for early detection of pancreatic cancer in plasma samples. A logistic regression model incorporating these metabolites, along with other clinical factors, significantly improved risk prediction compared to models without these markers. Continued research…

HPB & Spleen24 May 2024

Global Disparities in Outcomes of Pancreatic Surgery

Pancreatic surgery outcomes: Snapshot study across 67 countries reveals significantly higher postoperative mortality rates in low-to-middle-HDI nations compared to high-HDI counterparts. Over two-thirds of patients experienced complications, with a 90-day mortality rate of 5.4%. Failure-to-rescue rates were notably higher in lower-HDI countries. Collaborative efforts among…

BMC Surg24 May 2024

Postoperative Delirium After Hepatic Resection

Study on 80,070 patients undergoing hepatic resection reveals a 1.46% occurrence of postoperative delirium, with key risk factors including older age, male sex, depression, and various comorbidities. Patients with delirium had longer hospital stays, higher costs, and increased mortality rates than those without. Understanding these…

BMC Surg23 May 2024

Development and validation of nomograms for predicting survival and recurrence after hepatectomy in hepatocellular carcinoma patients

Despite discouragement for hepatectomy in intermediate/advanced hepatocellular carcinoma, nomograms were developed and validated for predicting survival and recurrence. These nomograms, based on 10 and 6 independent variables, respectively, outperformed conventional staging systems. They accurately stratified risk and can assist clinicians in personalized surgical decisions, prognosis…

HPB (Oxford)23 May 2024

Impact of Direct-Acting Antivirals on Liver Resection Outcomes for Hepatitis C-Related Hepatocellular Carcinoma

Direct-acting antivirals significantly improve outcomes of liver resection for hepatitis C-related hepatocellular carcinoma. Patients achieving sustained virological response (svr) had significantly better survival rates compared to those who did not. Introduction of direct-acting antivirals in the post-era resulted in superior survival outcomes. Svr was identified…

Hepatol Int23 May 2024

Comparing Robotic and Laparoscopic Liver Resection for Hepatocellular Carcinoma

Robotic liver resection (RLR) showcases longer operative times than laparoscopic liver resection (LLR) for hepatocellular carcinoma with no major disparities in other short-term outcomes. While overall survival remains alike, RLR promotes enhanced recurrence-free survival and a more proficient learning curve after the 11th case. RLR…

BMC Surg22 May 2024

Risk Factors for Delayed Gastric Emptying after Laparoscopic Pancreaticoduodenectomy

Delayed gastric emptying (DGE) after laparoscopic pancreaticoduodenectomy (LPD) was studied in 827 patients. Preoperative biliary drainage, blood loss, and major complications were significant risk factors for DGE. Higher BMI, soft pancreatic texture, and perioperative transfusion increased the risk of secondary DGE. Identifying at-risk patients can…