Category: HPB & Spleen

Redefining Surgery for Widespread Biliary Malignancy: A Survival Analysis

Researchers explored the impact of hepatopancreaticoduodenectomy (HPD), a radical surgery for biliary carcinoma, on survival in patients with widespread cancer. Of the 54 patients who underwent HPD, 89% achieved R0 resection, significantly improving survival with a median of 36.9 months. Pathological portal vein involvement was identified as an independent prognostic factor. Those with peripancreatic lymph […]

Disparities in Pancreatic Cancer Surgery: Minority Serving Hospitals Face Treatment Challenges

A study exploring the surgical treatment of resectable pancreatic adenocarcinoma in minority serving hospitals (MSH) revealed significant disparities. Patients at MSH were less likely to undergo surgical resection, facing unique barriers, and leading to increased mortality among those who did. These findings highlight the urgent need for targeted interventions to improve the care provided to […]

MRE Model Predicts Hepatic Decompensation in NAFLD Patients

A multicenter study harnessed Magnetic Resonance Elastography (MRE) to create a prediction model for hepatic decompensation in Non-Alcoholic Fatty Liver Disease (NAFLD) patients. This model, which combines MRE data with clinical factors like age, albumin, aspartate aminotransferase, and platelets, demonstrated excellent accuracy in forecasting the risk of hepatic decompensation over 3- and 5-year periods. The […]

Marking Small Liver Tumors Before Surgery: Will It Improve Resection?

To enhance the precision of small liver tumor removal, a phase II study in Japan will evaluate preoperative marking’s effectiveness. Patients with liver tumors ≤15 mm requiring hepatectomy will undergo microcoil placement near the tumor using either the percutaneous or transvascular approach. The study aims to determine the successful resection rate, with secondary endpoints including […]

Endoscopic Ultrasound-guided Nerve Block Shows Promise in Easing Pancreatic Cancer Pain

In a network meta-analysis of ten randomized controlled trials, researchers assessed the effectiveness of endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) in addition to medical management for abdominal pain in unresectable pancreatic cancer. Results favored EUS-CPN combined with medical management, showing significantly reduced pain intensity at 4 and 12 weeks compared to medical management alone or […]

Pancreatic Cancer on the Rise Globally: Factors and Future Projections

Researchers analyzed data from 2020 to 2040 to understand the trends in pancreatic cancer (PC) incidence and mortality worldwide. PC is linked to higher socioeconomic status, with Asia, especially China, bearing the greatest burden. Among age groups, those aged 65 and older are most affected, except in countries with medium and low human development indices […]

Factors Influencing Liver Remodeling After Right Hepatectomy

Researchers investigated the volumetric changes in the left liver after right hepatectomy and the factors influencing the degree of hypertrophy and severe post-hepatectomy liver failure (PHLF). After right hepatectomy, the left liver remnant exhibited a 25% hypertrophy with varying growth rates. Factors like gender, middle hepatic vein resection, and standardized future liver remnant influenced hypertrophy. […]

Using Allogeneic Vessels in Pancreaticoduodenectomy: Risk of Portal Vein Thrombosis and Impact on Prognosis

This study delves into the use of allogeneic vessels (AV) in pancreaticoduodenectomy (PD) with portal vein resection (PVR) and its relationship with portal vein thrombosis (PVT). The findings reveal that PVT is notably prevalent, especially in cases involving AV reconstructions. Independent risk factors for PVT include diabetes, the surgical procedure performed, and AV reconstruction. Furthermore, […]

Diverse Asian American Groups Show Varying Pancreatic Cancer Survival Rates

This study delves into pancreatic cancer outcomes in the disaggregated Asian American, Native Hawaiian, and Pacific Islander (AANHPI) population, which is often underrepresented in scientific research. Analyzing data from 296,448 patients, it reveals that AANHPI patients, as a whole, exhibited better median survival than Caucasians and African Americans. Notably, survival rates varied among AANHPI subpopulations, […]

Robotic Hepatectomy Shows Promise in Treating Malignant Liver Diseases

This groundbreaking study analyzed the outcomes of robotic hepatectomy for five major malignant liver diseases. Among the 210 patients who underwent this procedure, including cases like colorectal liver metastases and hepatocellular carcinoma, the results were promising. A favorable 5-year overall survival benefit was observed across these disease processes. The robotic platform demonstrated its prowess in […]