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Early drain removal (EDR) after pancreaticoduodenectomy (PD) is superior to late drain removal (LDR) in reducing major morbidity and shortening length of stay. While the difference in postoperative pancreatic fistula rates was not statistically significant, EDR showed lower rates of major morbidity and shorter length…
Short-term postoperative outcomes of lymphadenectomy for cholangiocarcinoma, hepatocellular carcinoma, and colorectal liver metastases were analyzed in 3456 patients undergoing liver resection. Lymphadenectomy was performed in 16% of cases, with the highest rate seen in robotic-assisted resections. However, it was associated with an increased risk of…
Adjuvant chemotherapy (AC) shows a significant survival advantage in patients with resected gallbladder adenocarcinoma, according to a retrospective cohort analysis. Factors like age, tumor grade, and stage were identified as independent prognostic factors. Poor/undifferentiated tumor histology, higher tumor stage, and lymph node involvement were also…
Laparoscopic radical antegrade modular pancreatosplenectomy (RAMPS) showed significantly higher rates of R0 resection (91.7% vs. 69.2%) and similar intraoperative blood loss and operative time compared to laparoscopic distal pancreatectomy with splenectomy. Both procedures had similar perioperative complication rates. The study demonstrates that laparoscopic RAMPS is…
Pancreatic ductal adenocarcinoma patients exhibit varied responses to therapy, with molecular subtyping revealing classical and basal-like subtypes, the latter associated with poorer outcomes. Two main tumor subtypes were identified, along with high-risk stromal subtypes linked to worse survival. Superior survival was seen with classical subtype.…
Unplanned conversion during laparoscopic liver resection for hepatocellular carcinoma is associated with higher blood loss, transfusion rate, hospital stay, and postoperative complications. However, the 5-year overall survival rate was similar in patients who underwent unplanned conversion and those who underwent laparoscopic liver resection.
Patients with gallbladder cancer presenting with acute cholecystitis had a 20% overall 5-year survival rate, with stage-specific survival rates varying. A third of patients with gallbladder cancer presented with acute cholecystitis but did not experience significantly different survival outcomes compared to other presentations. Age, gender,…
After left pancreatectomy for pancreatic adenocarcinoma, patients with a perioperative platelet count ratio (PPR) ≥ 1.5 had significantly longer median overall survival (OS) compared to those with PPR < 1.5 (40 months vs. 20 months). PPR was identified as a biomarker for predicting long-term survival…
In periampullary cancer patients undergoing pancreatoduodenectomy, anomalies in the right hepatic artery (RHA) anatomy, including accessory or replaced RHAs, were observed in 16.3% of cases. However, when comparing outcomes with a propensity score-matched analysis, the presence of these anomalies did not significantly impact perioperative complications…
Perioperative dexamethasone did not significantly reduce postoperative complications within 30 days after pancreaticoduodenectomy, as evidenced by similar comprehensive complication index scores, major complications, and pancreatic fistula rates between the dexamethasone and placebo groups. However, in patients with a main pancreatic duct ≤3 mm, the dexamethasone…
