Individuals with lower polygenic risk scores experienced better weight loss outcomes after bariatric surgery compared to those with higher scores, especially in patients undergoing roux-en-y gastric bypass. Genetic background, assessed through polygenic risk scores, plays a significant role in long-term weight loss post-surgery, alongside factors like sex, age, and initial BMI. These findings suggest the […]
Category: Metabolic and Bariatric Surgery
Sleeve Gastrectomy Promotes Type 2 Diabetes Remission
Significant weight loss and remission of type 2 diabetes mellitus were observed in patients post-sleeve gastrectomy. Patients exhibited low citrulline and high I-FABP levels preoperatively, which normalized postoperatively. The study found a positive correlation between the I-FABP/citrulline ratio and weight, BMI, glucose, insulin, and c-peptide levels. Sleeve gastrectomy not only improves enteroendocrine function but also […]
Sex Differences in Weight Loss and Complications Post Bariatric Surgery
Male patients had slightly greater weight loss and higher complication rates compared to females following bariatric surgery. However, these differences were not clinically significant. Providers should consider referring males earlier for surgery given their higher comorbidity rates. This study highlights the need to assess sex differences in outcomes to personalize bariatric care effectively. Journal Article […]
Effectiveness of Bariatric Surgery on Ovulation Rates in Women with Polycystic Ovary Syndrome
Findings from the BAMBINI trial show that bariatric surgery significantly increased rates of spontaneous ovulation in women with polycystic ovary syndrome (PCOS) and obesity compared to medical care. The surgical group had 2.5 times more ovulations than the medical group, indicating greater efficacy in improving fertility prospects. Although complications were more frequent in the surgery […]
Pylorus Preservation in SG + LoopDJB Reduces Hypoalbuminemia Compared to OAGB
One anastomosis gastric bypass (OAGB) and sleeve gastrectomy with loop duodenojejunal bypass (SG + LoopDJB) demonstrate similar weight loss, type 2 diabetes remission, and lipidemia improvements at 1 year post-operation. OAGB presents higher hypoalbuminemia but lower gastroesophageal reflux disease symptoms compared to SG + LoopDJB. Pylorus preservation in SG + LoopDJB may reduce hypoalbuminemia risk, […]
Preoperative Risk Factors for Early Postoperative Bleeding after Roux-en-Y Gastric Bypass Surgery
Preoperative risk factors, including age, gender, hypertension, and revisional bariatric surgery, are associated with early postoperative bleeding after Roux-en-Y gastric bypass. Further primary studies are needed to explore additional risk factors for this complication, aiding in patient risk stratification and optimization. Male gender was identified as a significant predictor of early postoperative bleeding, emphasizing the […]
Preoperative Very Low-Energy Diets in Obese Patients Undergoing Non-Bariatric Surgery
Patients with obesity undergoing surgery face higher risks, mitigated by preoperative weight loss strategies like very low-energy diets (VLEDs) commonly used in bariatric surgery. However, VLEDs’ application in non-bariatric surgery is understudied. A pilot trial is needed to assess feasibility and safety for a larger trial. The upcoming PREPARE pilot trial will gather crucial data […]
Long-Term Impact of Metabolic Bariatric Surgery on Cardiovascular Events
Metabolic bariatric surgery shows enduring weight reduction and improvement in obesity-related comorbidities. Both OAGB and SADJB-SG procedures lead to significant improvements in BMI, diabetes, hypertension, and dyslipidemia over three years. Patients also experience a substantial reduction in 10-year MACE, stroke, and atherosclerotic CVD risks. These findings highlight the effectiveness of OAGB and SADJB-SG in metabolic […]
Impact of Recurrent Weight Gain on Comorbid Conditions Progression Post-Laparoscopic Sleeve Gastrectomy
Recurrent weight gain after laparoscopic sleeve gastrectomy was studied in 122 patients over 2-7 years, showing significant weight loss and comorbidity remission rates. Diabetes, hypertension, and dyslipidemia had substantial remission rates, while a recurrent weight gain ≥ 20% of maximum weight loss indicated comorbidity progression. Healthcare providers can use these findings to implement targeted management strategies for […]
Higher Intraoperative Blood Pressure Reduces Post-Bariatric Hemorrhage
Increasing intraoperative blood pressure to 150 mmHg systolic, without staple line reinforcement, significantly reduces post-bariatric hemorrhagic complications. A retrospective study of 438 patients found a reduction in postoperative bleeding rates from 10% to 5% after implementing this intervention, with a decrease in revisional surgery for bleeding. The method shows promise in improving outcomes without additional […]
