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Best Papers in General Surgery
The five that matter, every day.
In a controlled trial involving 150 patients, intraoperative controlled hyperventilation significantly reduced the incidence of shoulder pain after laparoscopic cholecystectomy, with pain rates dropping from 60% to 36%. The group experienced shorter pain duration and intensity, along with improved surgical conditions, reflected by reduced operation…
Intraoperative blood loss (IBL) ratios were found to predict local recurrence after curative resection in stage I-III colorectal cancer patients. Higher IBL ratios correlated with a greater risk of early local recurrence within two years post-surgery. Multivariate analysis indicated that factors such as anastomotic leakage…
An international multicenter study validated the Iwate difficulty scoring system (DSS) for laparoscopic liver resections (LLR) across both its four difficulty levels and 12-point difficulty index. Analyzing 14,759 patients, researchers found that intraoperative and postoperative outcomes—such as operation time, blood loss, and complications—worsened significantly with…
A nutrition-based nomogram has been developed to predict the risk of intra-abdominal infection (IAI) after D2 radical gastrectomy for gastric cancer. An analysis of 404 patients identified key indicators, including the NRS2002 score, fasting blood glucose, and multi-visceral resection, associating them with IAI risk. The…
Significant preoperative amino acid elevations were found in gastric cancer patients. Post-surgery, many amino acids decreased but were partially restored with nutritional intervention, with some levels surpassing preoperative values. However, methionine and glutamine remained lower than in healthy individuals. Correlations were identified between specific amino…
EUS-guided gallbladder drainage (EUS-GBD) is emerging as a safe, effective solution for managing acute cholecystitis in patients unfit for surgery. Recent findings indicate improved technical and clinical outcomes, especially with the use of lumen-apposing metal stents, which facilitate direct gallbladder inspection. The study emphasizes the…
A meta-analysis of 1500 patients found that lactated Ringer's (LR) solution significantly reduces the risk of progressing to moderate-to-severe acute pancreatitis compared to normal saline (NS), with an odds ratio of 0.48. Patients receiving LR also experienced shorter hospital stays and lower ICU admission rates.…
A deep learning-based clinical-radiomics model has shown strong predictive capability for durable clinical benefit (dcb) in patients with potentially convertible hepatocellular carcinoma receiving immune checkpoint inhibitors (ICIs). The model achieved an area under the curve (AUC) of 0.96 in training and 0.88 in testing, accurately…
A novel robotic approach for the retrosternal route in gastric conduit reconstruction has demonstrated safety and efficiency. In a study involving 43 esophageal cancer patients, the median time for creating this route was just nine minutes, with no incidences of pleural injury or postoperative hemorrhage…
Recent advancements in fluorescence-guided surgery provide significant improvements in identifying hepatocellular carcinoma (HCC) lesions. Indocyanine green has been essential for delineating tumor boundaries yet lacks the ability to differentiate between benign and malignant tumors. This review discusses clinical applications and emerging alternatives, such as aggregation-induced…
