Neoadjuvant docetaxel-based chemotherapy followed by en bloc resection is an effective treatment for locally advanced esophageal adenocarcinoma. Results from a 15-year retrospective analysis showed that both docetaxel/cisplatin/5FU and 5FU/leucovorin/oxaliplatin/docetaxel regimens achieved similar survival outcomes. A high percentage of patients completed the neoadjuvant cycles, and the majority achieved an R0 resection. Although the median lymph node […]
Category: General Surgery
Unhoused Patients Experience Numerous Challenges in Surgical Care
Unhoused patients face significant barriers in receiving surgical care, leading to poorer outcomes compared to the general population. This qualitative analysis of 26 interviews with clinicians revealed five key themes: challenges in meeting preoperative requirements, housing status influencing minor care decisions, negative postoperative experiences for unhoused patients, imperfect discharge options leading to inadequate postoperative care, […]
Robotic Approach for Ventral Hernia Repair Lowers Wound Morbidity in High-Risk Patients
A propensity score analysis was conducted using the abdominal core health quality collaborative (ACHQC) database to evaluate the impact of robotic approach on wound morbidity in high-risk patients undergoing retromuscular ventral hernia repair. After matching patients for each approach, it was found that the robotic approach resulted in decreased rates of surgical site infections (SSIs) […]
Risk-stratified Pathways Improve Post-Hepatectomy Outcomes
Risk-stratified post-hepatectomy pathways (rsphps) were analyzed in a study of 1,354 patients. The pathways effectively stratified hepatectomy patients based on their risk of early postoperative events. The results showed that post-pathway implementation led to shorter hospital stays and decreased the need for readmission and interventional radiology procedures. rsphps can reliably predict the most frequent time […]
Incidentally detected T2 gallbladder cancer associated with poorer outcomes compared to upfront surgery
Incidentally detected T2 gallbladder cancer (pt2 GBC) has been found to have significantly worse outcomes compared to similarly staged patients who undergo upfront radical cholecystectomy. A retrospective analysis of 425 cases revealed that patients with incidentally detected tumors had higher rates of locoregional, liver, and abdominal wall recurrences. The five-year disease-free survival rate was lower […]
Comparison of outcomes between re-resected incidental gallbladder carcinoma and primary gallbladder carcinoma
Patients with re-resected incidental gallbladder carcinoma (rrigbc) had better prognosis and were at earlier tumor stage compared to those with primary radically resected gallbladder carcinoma (prgbc). Subgroup analysis revealed similar outcomes for patients with T1-2 tumors in both groups. However, patients with T3-4 tumors in the prgbc group had significantly worse prognosis. Incidental gallbladder carcinoma […]
Calcium Channel Blockers Improve Survival in Pancreatic Cancer Patients Receiving Neoadjuvant Chemotherapy
Calcium channel blockers (CCB) were found to be associated with improved overall survival in pancreatic cancer patients undergoing neoadjuvant chemotherapy and resection. A retrospective study of 6,223 patients showed that CCB prescription was specifically beneficial in the subgroup receiving neoadjuvant chemotherapy, reflecting the chemosensitizing effect observed in laboratory studies. These findings suggest that patients receiving […]
Higher likelihood of non-home discharge in pancreatic cancer patients aged 80 years and above
In a study analyzing pancreatic cancer patients aged 80 years and above, it was found that non-home discharge after pancreatoduodenectomy (PD) was more than twice as likely to occur in this age group compared to those aged 65-79 years. Comorbidity factors such as COPD, hypertension, heart failure, and lower preoperative albumin were significantly associated with […]
The impact of diabetes mellitus on outcomes in patients undergoing surgical pancreatectomy for pancreatic diseases
A retrospective analysis of 370 patients who underwent pancreatic resection surgery in Austria revealed that the incidence of postoperative diabetes mellitus (postopdm) was 29%. Postopdm occurred significantly more frequently in patients with malignant pancreatic diseases compared to benign diseases (31.3% vs. 16.7%). The study highlights the prominence of diabetes mellitus as a risk factor for […]
Age-Dependent Disparities in General Surgery Outcomes: Variations in Hospital Performance
Hospital performance for general surgery varies between younger and older adults, with in-hospital mortality rates showing significant differences. Failure-to-rescue rates drive the variation in older adults, while both complication and failure-to-rescue rates contribute to high mortality rates in younger adults. Correlations between observed-to-expected mortality ratios suggest distinct hospital performance in each age group. Low-mortality hospitals […]