Indirect signs of portal hypertension (pht) don’t raise complications risk in hepatocellular carcinoma (HCC) patients undergoing liver resection (LR). However, in patients with hepatic venous pressure gradient (HVPG) ≥10 mmHg, LR significantly increases overall morbidity and liver-related complications risk. Transjugular HVPG assessment is crucial for LR decisions, with a minimally invasive approach showing favorable outcomes, […]
Category: General Surgery
Pathological Response is not a Reliable Surrogate for Overall Survival in Neoadjuvant Studies for Esophageal Cancer
The study evaluates the validity of using pathological response as a surrogate marker for overall survival (OS) in neoadjuvant studies for esophageal cancer. A meta-analysis comprising 40 trials and 55,344 patients shows that the surrogacy between pathological complete response (PCR) and OS is moderate. The study establishes a lack of surrogacy at the trial level […]
Accurate Prediction of Anti-TNF Treatment Failure in Perianal Crohn’s Disease Using MRI-Based Model
Researchers developed an MRI-based prediction model for anti-TNF treatment failure in perianal Crohn’s disease. The model, based on clinical and radiologic parameters, accurately predicts the likelihood of treatment failure and outperforms existing imaging-based indices. The study included 221 patients, with treatment failure occurring in 46% of cases. The prediction model included age at diagnosis, time […]
Predictive factors for successful same-day discharge following minimally invasive colorectal surgery
A prospective cohort study conducted at a tertiary colorectal center aimed to identify predictive factors for successful same-day discharge following minimally invasive colorectal surgery. Out of 175 patients, 161 (78.5%) were discharged on the day of surgery without complications, while 44 (21.5%) experienced same-day discharge failure. Factors associated with failure included higher comorbidities, prolonged post-anesthesia […]
Nonoperative Management Shows Promising Results for Anal Adenocarcinoma
Anal adenocarcinoma can be effectively treated with total neoadjuvant therapy and nonoperative management, according to a retrospective analysis conducted at a comprehensive cancer center. The study included 70 patients, out of which 77% received neoadjuvant therapy. Patients who underwent total neoadjuvant therapy had a higher proportion of successful watch-and-wait management compared to those who received […]
Temporary Stoma Does Not Impact Long-Term Functional Outcomes in Rectal Cancer Patients
Rectal cancer patients who undergo surgical resection with or without a temporary stoma were compared in terms of long-term functional outcomes. The study, conducted at seven Dutch hospitals with 656 patients, found that those with a temporary ileostomy experienced less constipation but more fecal incontinence and major low anterior resection syndrome compared to those without […]
No Significant Hernia Recurrence, but Increased Complications: Impact of Smoking on Minimally Invasive Paraesophageal Hernia Repair Outcomes
The impact of active smoking on outcomes of minimally invasive paraesophageal hernia repair (PEHR) was assessed in this cohort study. There was no significant difference in rates of death or serious morbidity (DSM) or hernia recurrence between smokers and non-smokers. However, on further analysis using the National Surgical Quality Improvement Program (NSQIP) database, smoking status […]
Increased Use of Z Codes in Ambulatory Surgery Reveals Socioeconomic Needs
Researchers analyzed data from 41,827 ambulatory surgery encounters from 2016 to 2019 and found a 16.1% increase in the use of International Statistical Classification of Diseases and Health Related Problems, tenth revision (ICD-10) Z codes. The most commonly documented health determinants were multiparity or unwanted pregnancy, homelessness, and incarceration. The study suggests that rates of […]
Gender Disparities in Academic Leadership and Professional Rank in Surgery
The study found that there is a significant gender disparity in academic leadership positions among surgeons, despite women holding more advanced non-doctoral degrees. Female surgeons were more likely to have advanced degrees than their male counterparts, but they were less likely to hold the rank of professor and more likely to hold the rank of […]
Effect of Procedural Volume on Adverse Outcomes in Gastric Endoscopic Submucosal Dissection
A nationwide population-based study investigated the influence of procedural volume on the outcome of gastric endoscopic submucosal dissection (ESD) for gastric cancer or adenoma. The study included 88,687 patients who underwent 94,246 procedures between November 2011 and December 2017. The results showed that high- and medium-volume centers had a significantly lower risk of adverse outcomes […]