A retrospective analysis comparing direct percutaneous endoscopic jejunostomy (DPEJ) tube placement with laparoscopic (Lap-J) and open laparotomy (Open-J) surgical methods revealed similar procedural success rates and complication rates in all three approaches. However, patients who underwent DPEJ experienced significantly lower rates of tube dysfunction within 90 days compared to surgical groups, primarily due to reduced […]
Category: General Surgery
Self-expanding metal stents for cholangiocarcinoma: higher clinical success rates but also higher stent-specific adverse events
This retrospective study analyzes the optimal biliary stenting strategy for palliation in cholangiocarcinoma patients. It found that self-expanding metal stents (SEMS) and plastic stents (PS) within SEMS had higher clinical success rates but also higher stent-specific adverse events. Removing PS may facilitate percutaneous biliary drainage (PTBD). Double-pigtail stents had fewer complications compared to straight PS. […]
Gasless Single-Incision Endoscopic Surgery for Lateral Neck Dissection in Papillary Thyroid Cancer: Scarless Cervical Appearence and Good Efficacy
Gasless single-incision endoscopic surgery via subclavicular approach (ESSA) is a safe and effective procedure for lateral neck dissection in patients with papillary thyroid cancer. Results showed that ESSA had comparable lymph node yield to video-assisted endoscopic surgery (VAES) and open surgery (OP), while also resulting in lower swallowing impairment scores and higher cosmetic satisfaction rates. […]
Patients’ Preferences for Decision Counseling in Esophageal Cancer
Patients with esophageal cancer were offered decision counseling (dc) either before or after neoadjuvant chemoradiotherapy (ncrt) to reflect on their treatment preferences. Interviews with patients revealed that those who received counseling before ncrt were satisfied with the timing, while some patients who received counseling after ncrt would have preferred it earlier. Overall, patients had positive […]
Ex Vivo Expanded Allogeneic Mesenchymal Stem Cells Provide Durable Treatment for Fistulizing Crohn’s Disease
The results of three phase Ib/IIa clinical trials show that treatment with ex vivo expanded allogeneic bone marrow-derived mesenchymal stem cells is safe and effective for severe perianal, rectovaginal, and peripouch fistulizing Crohn’s disease. At 6 months, 83.3% of perianal, 33.3% of rectovaginal, and 30.8% of pouch fistula treatment cohorts achieved combined clinical and radiographic […]
The Impact of Surgical-Oncologic Textbook Outcome in Pancreatic Ductal Adenocarcinoma
The study evaluated surgical-oncologic textbook outcomes in patients with stage I to III pancreatic ductal adenocarcinoma using national registries. The results showed that over 50% of patients achieved surgical-oncologic textbook outcomes in both the US and Germany. Patients who failed to achieve these outcomes had significantly impaired survival rates. The median overall survival was higher […]
Outcome of Tailored Surgery for Chronic Pancreatitis Based on Pancreatic Morphology
The nationwide study analyzed the use and outcome of tailored surgical treatment for symptomatic chronic pancreatitis (CP) based on pancreatic morphology. The analysis revealed that surgical drainage procedures, such as extended lateral pancreaticojejunostomy, resulted in the best safety profile and excellent functional outcomes. Mortality rates were lower and major complications, pancreatic fistula, surgical reinterventions, and […]
Complete mesocolic excision in right colon cancer: Higher lymph node yield and improved surgical quality
Interim analysis of a randomized Phase III trial comparing complete mesocolic excision (CME) with conventional surgery for right colon cancer showed that CME was associated with a significantly higher lymph node yield (25 vs. 20) and improved surgical quality indicators. No differences were observed in complications, mortality, or surgery duration. Hospital stay was even shorter […]
Smoking status predicts treatment failure in anti-reflux mucosectomy for gastroesophageal reflux disease
The study evaluated the outcomes and predictors of treatment failure in patients undergoing anti-reflux mucosectomy for gastroesophageal reflux disease. The results showed that the procedure significantly improved quality of life, with symptom improvement and resolution in a majority of patients. However, symptom resolution did not always correlate with objective reflux control. Current smoking status was […]
Advantages of Retroperitoneal Laparoscopic Adrenalectomy for Small Tumors
A comparative study was conducted to compare the effectiveness and safety of transabdominal and retroperitoneal laparoscopic adrenalectomies. The study involved 472 patients, with laparoscopic transabdominal adrenalectomies (LTA) being the preferred approach for most surgeons. It was found that retroperitoneal adrenalectomies (RPA) had advantages in terms of surgery time, blood loss, post-op pain, and recovery for […]